C1q binding to surface-bound IgG is stabilized by C1r2s2 proteases
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DOI: 10.1073/pnas.2102787118
Abstract: Significance Antibody-dependent complement activation plays a major role in various pathophysiological processes in our body, including infection, inflammation, autoimmunity, and transplant rejection. In order to activate complement, antibodies should bind to target cells and recruit… read more here.
Keywords: surface bound; bound igg; c1r2s2 proteases; igg ... See more keywords