Aconicatisulfonines A and B, Analgesic Zwitterionic C20-Diterpenoid Alkaloids with a Rearranged Atisane Skeleton from Aconitum carmichaelii.
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DOI: 10.1021/acs.orglett.9b02479
Abstract: Two sulfonated C20-diterpenoid alkaloid iminiums with a novel skeleton, named aconicatisulfonines A (1) and B (2), respectively, were isolated from a water extract of the Aconitum carmichaelii lateral roots. Structures of 1 and 2 were… read more here.
Keywords: skeleton; c20 diterpenoid; aconitum carmichaelii;
Discovery of C20-Diterpenoid Alkaloid Kobusine Derivatives Exhibiting Sub-G1 Inducing Activity
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DOI: 10.1021/acsomega.2c02363
Abstract: Although many diterpenoid alkaloids have been evaluated recently for antiproliferative activity against human cancer cell lines, little data have been offered relating to the antiproliferative effects of hetisine-type C20-diterpenoid alkaloids, such as kobusine (1), likewise… read more here.
Keywords: diterpenoid alkaloid; activity; c20 diterpenoid; kobusine derivatives ... See more keywords
Two new bis-C20-diterpenoid alkaloids with anti-inflammation activity from Aconitum bulleyanum
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DOI: 10.1080/10286020.2018.1439024
Abstract: Abstract Two new bis-C20-diterpenoid alkaloids, bulleyanines A and B (1 and 2), were isolated from Aconitum bulleyanum. Their structures were elucidated by comprehensive spectroscopic analyses including UV, IR, MS, 1D and 2D NMR. Biological activity… read more here.
Keywords: diterpenoid alkaloids; new bis; two new; c20 diterpenoid ... See more keywords
A new denudatine type C20-diterpenoid alkaloid from Aconitum sinchiangense W. T. Wang
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DOI: 10.1080/14786419.2017.1410814
Abstract: Abstract A new denudatine-type C20-diterpenoid alkaloid, designated as sinchianine (1), together with eight known diterpenoid alkaloids, 12-acetyl-12-epi-napelline (2), 12-epi-napelline (3), neoline (4), talatisamine (5), 14-O-acetylsenbusine A (6) and benzoylaconine (7), songorine (8) and aconitine (9),… read more here.
Keywords: type c20; new denudatine; aconitum sinchiangense; denudatine type ... See more keywords