Chlorogenic acid protects human chondrocyte C28/I2 cells from oxidative stress-induced cell death through activation of autophagy.
Sign Up to like & getrecommendations! Published in 2021 at "Life sciences"
DOI: 10.1016/j.lfs.2021.119968
Abstract: AIMS The development of osteoarthritis (OA), the most common form of arthritis, is commonly associated with oxidative stress. Indeed, the lack of antioxidant responses largely increases OA incidence. OA is a leading cause of disability… read more here.
Keywords: c28 cells; stress; chlorogenic acid; cell ... See more keywords
Selenium‐sensitive miRNA‐181a‐5p targeting SBP2 regulates selenoproteins expression in cartilage
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DOI: 10.1111/jcmm.13858
Abstract: Selenium (Se) deficiency brings about defects in the biosynthesis of several selenoproteins and has been associated with aberrant chondrogenesis. Selenocysteine (Sec) Insertion Sequence (SECIS) and SECIS binding protein 2 (SBP2) interaction is a very critical… read more here.
Keywords: sbp2; selenium sensitive; c28 cells; expression ... See more keywords
Cinnamaldehyde Induces the Expression of MicroRNA-1285-5p and MicroRNA-140-5p in Chondrocytes to Ameliorate the Apoptosis and Inflammatory Response.
Sign Up to like & getrecommendations! Published in 2023 at "Cartilage"
DOI: 10.1177/19476035221114858
Abstract: OBJECTIVE Cinnamaldehyde (CA) is an active ingredient of Wenyang Tongluo capsule. This study was performed to investigate the function of CA on human chondrocytes. DESIGN Different doses of CA were used to treat C28/I2 cells,… read more here.
Keywords: mir 1285; apoptosis; mir 140; c28 cells ... See more keywords