2-D08 treatment regulates C2C12 myoblast proliferation and differentiation via the Erk1/2 and proteasome signaling pathways
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Muscle Research and Cell Motility"
DOI: 10.1007/s10974-021-09605-x
Abstract: SUMOylation is one of the post-translational modifications that involves the covalent attachment of the small ubiquitin-like modifier (SUMO) to the substrate. SUMOylation regulates multiple biological processes, including myoblast proliferation, differentiation, and apoptosis. 2-D08 is a… read more here.
Keywords: c2c12 myoblast; treatment; differentiation; proliferation differentiation ... See more keywords
Berberine protects against cytokine-induced inflammation through multiple pathways in undifferentiated C2C12 myoblast cells.
Sign Up to like & getrecommendations! Published in 2019 at "Canadian journal of physiology and pharmacology"
DOI: 10.1139/cjpp-2018-0653
Abstract: Obesity is associated with skeletal muscle insulin resistance and the development of metabolic syndrome. Undifferentiated skeletal muscle cells are sensitive to oxidative stress. Berberine hydrochloride (BBR) improves insulin resistance and exhibits anti-inflammatory properties. However, the… read more here.
Keywords: c2c12 myoblast; cytokine induced; activated protein; undifferentiated c2c12 ... See more keywords