Heterologous Production of the C33-C45 Polyketide Fragment of Anticancer Apratoxins in a Cyanobacterial Host.
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DOI: 10.1021/acs.orglett.3c00462
Abstract: A polyketide synthase subcluster of cytotoxic apratoxin A was isolated from a Moorena bouillonii environmental DNA library and engineered with a thioesterase II domain for heterologous expression in the filamentous cyanobacterium Anabaena sp. PCC7120. Further… read more here.
Keywords: c33 c45; c45 polyketide; polyketide fragment; heterologous production ... See more keywords