Molecular Dynamic Simulations Reveal the Activation Mechanisms of Oxidation-Induced TRPV1
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DOI: 10.3390/ijms24119553
Abstract: Transient receptor potential vanilloid 1 (TRPV1), a non-selective cation channel, can be directly activated by oxidants through cysteine modification. However, the patterns of cysteine modification are unclear. Structural analysis showed that the free sulfhydryl groups… read more here.
Keywords: c387 c391; molecular dynamic; simulations reveal; dynamic simulations ... See more keywords