C3aR and C5aR1 act as key regulators of human and mouse β-cell function
Sign Up to like & getrecommendations! Published in 2017 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-017-2655-1
Abstract: AimsComplement components 3 and 5 (C3 and C5) play essential roles in the complement system, generating C3a and C5a peptides that are best known as chemotactic and inflammatory factors. In this study we characterised islet… read more here.
Keywords: function; human mouse; c3ar c5ar1;
Expression of complement C3, C5, C3aR and C5aR1 genes in resting and activated CD4+ T cells.
Sign Up to like & getrecommendations! Published in 2019 at "Immunobiology"
DOI: 10.1016/j.imbio.2018.12.004
Abstract: Complement activation is traditionally thought to occur in the extracellular space. However, it has been suggested that complement proteins are activated and function at additional locations. T cells contain intracellular stores of C3 and C5… read more here.
Keywords: complement; c3ar c5ar1; cd4 cells; expression ... See more keywords