Clostridium botulinum C3 Toxin for Selective Delivery of Cargo into Dendritic Cells and Macrophages
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DOI: 10.3390/toxins14100711
Abstract: The protein toxin C3bot from Clostridium botulinum is a mono-ADP-ribosyltransferase that selectively intoxicates monocyte-derived cells such as macrophages, osteoclasts, and dendritic cells (DCs) by cytosolic modification of Rho-A, -B, and -C. Here, we investigated the… read more here.
Keywords: cargo; clostridium botulinum; c3bote174q; selective delivery ... See more keywords