Distinguishing Neuromyelitis Optica Spectrum Disorders Subtypes: A Study on AQP4 and C3d Epitope Expression in Cytokine‐Primed Human Astrocytes
Sign Up to like & getrecommendations! Published in 2025 at "Glia"
DOI: 10.1002/glia.24675
Abstract: Neuromyelitis optica spectrum disorders (NMOSD) are severe autoimmune conditions affecting the central nervous system. In a subset of cases, no autoantibodies are detectable with the currently used routine assays. This study aimed to determine whether… read more here.
Keywords: epitope expression; neuromyelitis optica; c3d; human astrocytes ... See more keywords
Insights Into the Structure-Function Relationships of Dimeric C3d Fragments
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DOI: 10.3389/fimmu.2021.714055
Abstract: Cleavage of C3 to C3a and C3b plays a central role in the generation of complement-mediated defences. Although the thioester-mediated surface deposition of C3b has been well-studied, fluid phase dimers of C3 fragments remain largely… read more here.
Keywords: relationships dimeric; insights structure; c3d; function relationships ... See more keywords
Autoimmune Hemolytic Anemias: Classifications, Pathophysiology, Diagnoses and Management
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DOI: 10.3390/ijms25084296
Abstract: Autoimmune hemolytic anemias (AIHAs) are conditions involving the production of antibodies against one’s own red blood cells (RBCs). These can be primary with unknown cause or secondary (by association with diseases or infections). There are… read more here.
Keywords: c3d; igg; hemolytic anemias; dat ... See more keywords