Novel secondary mutations C56S and G149A confer resistance to HIV‐1 integrase strand transfer inhibitors
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DOI: 10.1016/j.antiviral.2018.01.013
Abstract: ABSTRACT Cabotegravir (CAB, S/GSK1265744) is an investigational second‐generation integrase strand transfer inhibitor (INSTI) with a chemical structure similar to dolutegravir. CAB is under development as a long‐acting injectable formulation for treatment of HIV‐1 infection and… read more here.
Keywords: integrase; c56s g149a; strand transfer; resistance ... See more keywords