The role of C5a-C5aR1 axis in bone pathophysiology: A mini-review
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.957800
Abstract: Bone remodeling is a physiological, dynamic process that mainly depends on the functions of 2 cell types: osteoblasts and osteoclasts. Emerging evidence suggests that complement system is crucially involved in the regulation of functions of… read more here.
Keywords: c5a; bone; role c5a; c5ar1 axis ... See more keywords
The C5a/C5aR1 Axis Contributes to the Pathogenesis of Acute Cystitis Through Enhancement of Adhesion and Colonization of Uropathogenic E. coli
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.824505
Abstract: Our previous work using a murine model of pyelonephritis demonstrated that the C5a/C5aR1 axis plays a pathogenic role in acute kidney infection. In this study, we report that the C5a/C5aR1 axis also plays a pathogenic… read more here.
Keywords: c5ar1; bladder; infection; c5ar1 axis ... See more keywords
C5a/C5aR1 Pathway Is Critical for the Pathogenesis of Psoriasis
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2019.01866
Abstract: Psoriasis is one of the most common chronic inflammatory skin diseases, affecting ~2% of the population. The lack of characterization of the pathogenesis of psoriasis has hindered efficient clinical treatment of the disease. In our… read more here.
Keywords: psoriasis; pathogenesis psoriasis; c5a c5ar1; c5ar1 ... See more keywords