C5a impairs phagosomal maturation in the neutrophil through phosphoproteomic remodeling
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DOI: 10.1172/jci.insight.137029
Abstract: Critical illness is accompanied by the release of large amounts of the anaphylotoxin, C5a. C5a suppresses antimicrobial functions of neutrophils which is associated with adverse outcomes. The signaling pathways that mediate C5a-induced neutrophil dysfunction are… read more here.
Keywords: phagosomal maturation; c5a impairs; phagosomal acidification; impairs phagosomal ... See more keywords