C5a–C5AR1 axis as a potential trigger of the rupture of intracranial aneurysms
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-53651-7
Abstract: Recent studies have indicated the involvement of neutrophil-mediated inflammatory responses in the process leading to intracranial aneurysm (IA) rupture. Receptors mediating neutrophil recruitment could thus be therapeutic targets of unruptured IAs. In this study, complement… read more here.
Keywords: c5a c5ar1; c5ar1; c5ar1 c5ar1; c5ar1 axis ... See more keywords
The role of C5a-C5aR1 axis in bone pathophysiology: A mini-review
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.957800
Abstract: Bone remodeling is a physiological, dynamic process that mainly depends on the functions of 2 cell types: osteoblasts and osteoclasts. Emerging evidence suggests that complement system is crucially involved in the regulation of functions of… read more here.
Keywords: c5a; bone; role c5a; c5ar1 axis ... See more keywords
The C5a/C5aR1 Axis Contributes to the Pathogenesis of Acute Cystitis Through Enhancement of Adhesion and Colonization of Uropathogenic E. coli
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.824505
Abstract: Our previous work using a murine model of pyelonephritis demonstrated that the C5a/C5aR1 axis plays a pathogenic role in acute kidney infection. In this study, we report that the C5a/C5aR1 axis also plays a pathogenic… read more here.
Keywords: c5ar1; bladder; infection; c5ar1 axis ... See more keywords