Neutraligands of C5a can potentially occlude the interaction of C5a with the complement receptors C5aR1 and C5aR2
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.30360
Abstract: The complement system is central to the rapid immune response witnessed in vertebrates and invertebrates, which plays a crucial role in physiology and pathophysiology. Complement activation fuels the proteolytic cascade, which produces several complement fragments… read more here.
Keywords: c5ar1 c5ar2; c5a; complement; interaction c5a ... See more keywords
Complement receptors C5aR1 and C5aR2 act differentially during the early immune response after bone fracture but are similarly involved in bone repair
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DOI: 10.1038/s41598-017-14444-3
Abstract: Severely injured patients frequently suffer compromised fracture healing because of systemic post-traumatic inflammation. An important trigger of the posttraumatic immune response is the complement anaphylatoxin C5a, which acts via two receptors, C5aR1 and C5aR2, expressed… read more here.
Keywords: c5ar1 c5ar2; fracture; receptors c5ar1; bone ... See more keywords