The C5a/C5aR2 axis promotes renal inflammation and tissue damage.
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DOI: 10.1172/jci.insight.134081
Abstract: C5a is a potent inflammatory mediator, which binds C5aR1 and C5aR2. Although pathogenic roles of C5a/C5aR1 axis in inflammatory disorders are well-documented, the roles for C5a/C5aR2 axis in inflammatory disorders and underlying mechanisms remain unclear.… read more here.
Keywords: c5ar2 axis; c5a; renal inflammation; c5a c5ar2 ... See more keywords