Articles with "c5ar2 axis" as a keyword



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The C5a/C5aR2 axis promotes renal inflammation and tissue damage.

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Published in 2020 at "JCI insight"

DOI: 10.1172/jci.insight.134081

Abstract: C5a is a potent inflammatory mediator, which binds C5aR1 and C5aR2. Although pathogenic roles of C5a/C5aR1 axis in inflammatory disorders are well-documented, the roles for C5a/C5aR2 axis in inflammatory disorders and underlying mechanisms remain unclear.… read more here.

Keywords: c5ar2 axis; c5a; renal inflammation; c5a c5ar2 ... See more keywords