Association between MTHFR C677T polymorphism and risk of coronary artery disease in the Chinese population: meta-analysis
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DOI: 10.1007/s00059-021-05087-2
Abstract: Previous studies have investigated the close association between the MTHFR C677T polymorphism and the risk of coronary heart disease (CAD) in the Chinese population. However, the results remain inconclusive. Therefore, this meta-analysis was performed to… read more here.
Keywords: mthfr c677t; c677t polymorphism; polymorphism risk;
Methylenetetrahydrofolate reductase C677T polymorphism, hypertension and risk of stroke: a prospective, nested case-control study
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Neuroscience"
DOI: 10.1080/00207454.2016.1183126
Abstract: Background: Hyperhomocysteinemia is a risk factor for cardiovascular disease. To date, limited prospective studies have examined the joint effects of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism, hyperhomocysteinemia and conventional vascular risk factors on risk of… read more here.
Keywords: risk; c677t; c677t polymorphism; risk stroke ... See more keywords
P3566Ambulatory blood pressure response to riboflavin supplementation in adults with the C677T polymorphism in the folate metabolising enzyme methylenetetrahydrofolate reductase (MTHFR)
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DOI: 10.1093/eurheartj/ehz745.0428
Abstract: Epidemiological evidence suggests that the C677T polymorphism in the folate metabolising enzyme MTHFR is associated with a 24–87% increased risk of hypertension. Riboflavin (a cofactor for MTHFR) can modify this phenotype, as demonstrated in a… read more here.
Keywords: riboflavin; response riboflavin; c677t polymorphism; riboflavin supplementation ... See more keywords
Association between Methylene-Tetrahydrofolate Reductase C677T Polymorphism and Human Immunodeficiency Virus Type 1 Infection in Morocco.
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DOI: 10.1093/labmed/lmac081
Abstract: Human immunodeficiency virus type 1 (HIV-1) infection varies substantially among individuals. One of the factors influencing viral infection is genetic variability. Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism is a genetic factor that has been correlated with… read more here.
Keywords: polymorphism; mthfr c677t; infection; association ... See more keywords
A possible synergistic effect of MTHFR C677T polymorphism on homocysteine level variations increased risk for ischemic stroke
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DOI: 10.1097/md.0000000000009300
Abstract: Background: Homocysteine (Hcy) plays an important role in vascular function and Hcy level contributes to pathogenesis of ischemic stroke (IS). MTHFR gene polymorphism may have effects on IS risks by influencing the Hcy metabolic pathway.… read more here.
Keywords: c677t polymorphism; mthfr c677t; hcy level; mthfr ... See more keywords
Impact of the MTHFR C677T polymorphism on blood pressure and related central haemodynamic parameters in healthy adults
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DOI: 10.1111/jhn.13061
Abstract: Abstract Background The C677T polymorphism in the gene‐encoding methylenetetrahydrofolate reductase (MTHFR) is associated with an increased risk of hypertension and cardiovascular disease. Riboflavin, the MTHFR cofactor, is an important modulator of blood pressure (BP) in… read more here.
Keywords: polymorphism; genotype; related central; c677t polymorphism ... See more keywords
P42 Association of c677t polymorphism of mthfr gene with hemostasis changes in adolescents with essential hypertension
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DOI: 10.1136/archdischild-2017-313273.130
Abstract: Background and aims It is known that thrombosis in adolescents with essential hypertension (EH) are rare, however pro-coagulation hemostatic changes are multifactorial and requires detailed study. One of the risk factors can be C677T polymorphism… read more here.
Keywords: mthfr gene; polymorphism mthfr; group; study ... See more keywords
Lack of association between methylenetetrahydrofolate reductase C677T polymorphism, HPV infection and cervical intraepithelial neoplasia in Brazilian women
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DOI: 10.1186/s12881-019-0831-x
Abstract: BackgroundCervical cancer has high prevalence and mortality rates in worldwide female population. Persistent infection by high-risk Human Papillomavirus (hr-HPV) is the main cause of this cancer. However, many environmental, genetical, and epigenetical cofactors can modulate… read more here.
Keywords: infection; c677t polymorphism; hpv; cancer ... See more keywords
Association of MTHFR gene C677T polymorphism with pregnancy outcome.
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DOI: 10.26355/eurrev_202301_30868
Abstract: OBJECTIVE The two objectives of the present study were to analyze the correlation between pregnancy outcomes and methylenetetrahydrofolate reductase (MTHFR) gene C677T polymorphism, and to provide evidence for clinical improvement of adverse pregnancy outcomes. PATIENTS… read more here.
Keywords: mthfr gene; group; gene c677t; pregnancy ... See more keywords
Methylenetetrahydrofolate Reductase Gene C677T Polymorphism–Dietary Pattern Interaction on Hyperhomocysteinemia in a Chinese Population: A Cross-Sectional Study
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DOI: 10.3389/fcvm.2021.638322
Abstract: Background and aim: Hyperhomocysteinemia (Hhcy) has been recognized as a risk factor of several chronic diseases. There is accumulating evidence that both genetic and dietary factors had a notable impact on the risk of Hhcy.… read more here.
Keywords: polymorphism dietary; methylenetetrahydrofolate reductase; pattern; c677t polymorphism ... See more keywords
MTHFR C677T polymorphism and cerebrovascular lesions in elderly patients with CSVD: A correlation analysis
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DOI: 10.3389/fgene.2022.987519
Abstract: Plasma homocysteine (Hcy) has been identified as a potential risk factor for cerebral small vessel disease. Cerebral small vessel disease (CSVD) leads to cognitive impairment, depression, and other symptoms and is a common disease in… read more here.
Keywords: polymorphism; elderly patients; mthfr c677t; mthfr ... See more keywords