C9orf72 and RAB7L1 regulate vesicle trafficking in amyotrophic lateral sclerosis and frontotemporal dementia
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DOI: 10.1093/brain/awx024
Abstract: A non-coding hexanucleotide repeat expansion in intron 1 of the C9orf72 gene is the most common cause of amyotrophic lateral sclerosis and frontotemporal dementia (C9ALS/FTD), however, the precise molecular mechanism by which the C9orf72 hexanucleotide… read more here.
Keywords: c9orf72 rab7l1; c9orf72; c9als ftd; vesicle trafficking ... See more keywords