Orexin‐A increases the firing activity of hippocampal CA1 neurons through orexin‐1 receptors
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.23975
Abstract: Orexins including two peptides, orexin‐A and orexin‐B, are produced in the posterior lateral hypothalamus. Much evidence has indicated that central orexinergic systems play numerous functions including energy metabolism, feeding behavior, sleep/wakefulness, and neuroendocrine and sympathetic… read more here.
Keywords: orexin; ca1 neurons; ca1; firing activity ... See more keywords
Effect of Selank on Spontaneous Synaptic Activity of Rat Hippocampal CA1 Neurons
Sign Up to like & getrecommendations! Published in 2017 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-017-3676-3
Abstract: Application of anxiolytic drug Selank to hippocampal slices increased the amplitude and discharge rate of spontaneous inhibitory postsynaptic currents in rat hippocampal pyramidal CA1 neurons. In some neurons, Selank-induced up-regulation of spontaneous inhibitory postsynaptic currents… read more here.
Keywords: ca1 neurons; selank spontaneous; effect selank; rat hippocampal ... See more keywords
Hydromorphone protects CA1 neurons by activating mTOR pathway
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2018.09.029
Abstract: Hydromorphone has been shown to play protective effect in rat glial cell. However, whether hydromorphone plays important roles in ischemia-reperfusion (IR) injury and the involved signaling pathway remains unclear. In this study, we detected whether… read more here.
Keywords: ca1 neurons; hydromorphone; pathway; activating mtor ... See more keywords
Long-range inhibitory intersection of a retrosplenial thalamocortical circuit by apical tuft-targeting CA1 neurons
Sign Up to like & getrecommendations! Published in 2019 at "Nature neuroscience"
DOI: 10.1038/s41593-019-0355-x
Abstract: Hippocampus, granular retrosplenial cortex (RSCg), and anterior thalamic nuclei (ATN) interact to mediate diverse cognitive functions. To identify cellular mechanisms underlying hippocampo–thalamo–retrosplenial interactions, we investigated the potential circuit suggested by projections to RSCg layer 1… read more here.
Keywords: ca1 neurons; rscg; range; circuit ... See more keywords
Chronic altered light–dark cycle differentially affects hippocampal CA1 and DG neuronal arborization in diurnal and nocturnal rodents
Sign Up to like & getrecommendations! Published in 2022 at "Chronobiology International"
DOI: 10.1080/07420528.2021.2023561
Abstract: ABSTRACT The hippocampus, an extension of the temporal part of the cerebral cortex, plays a crucial role in learning and memory. Structural and functional complexity within the hippocampus is greatly affected by a variety of… read more here.
Keywords: cycle; dark cycle; hippocampal ca1; light dark ... See more keywords
Rescue of hyperexcitability in hippocampal CA1 neurons from Mecp2 (-/y) mouse through surface potential neutralization
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0195094
Abstract: Hyperventilation is a known feature of Rett syndrome (RTT). However, how hyperventilation is related to other RTT symptoms such as hyperexcitability is unknown. Intense breathing during hyperventilation induces hypocapnia and culminates in respiratory alkalosis. Alkalinization… read more here.
Keywords: ca1 neurons; hyperexcitability; excitability; surface potential ... See more keywords
Intraarterial anti-leptin therapy via ICA protects ipsilateral CA1 neurons subjected to ischemia and reperfusion
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0261644
Abstract: Background Brain reperfusion following an ischemic event is essential for tissue viability, however, it also involves processes that promote neuronal cell death. We have recently shown that local expression of the hormone leptin in cardiovascular… read more here.
Keywords: ca1 neurons; leptin; reperfusion; leptin antagonist ... See more keywords