A cellular protection racket: How lysosomal Ca2+ fluxes prevent kidney injury.
Sign Up to like & getrecommendations! Published in 2020 at "Cell calcium"
DOI: 10.1016/j.ceca.2020.102328
Abstract: LC3-lipidation is activated by lysosomal damage by mechanisms that are unknown and divergent from canonical autophagy. In this study, Nakamura et al, show that lysosomal damage induced by lysosomotropic agents or oxalate in renal proximal… read more here.
Keywords: protection racket; ca2 fluxes; cellular protection; racket lysosomal ... See more keywords
Shaped by leaky ER: Homeostatic Ca2+ fluxes
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.972104
Abstract: At any moment in time, cells coordinate and balance their calcium ion (Ca2+) fluxes. The term ‘Ca2+ homeostasis’ suggests that balancing resting Ca2+ levels is a rather static process. However, direct ER Ca2+ imaging shows… read more here.
Keywords: homeostatic ca2; resting ca2; leaky homeostatic; ca2 fluxes ... See more keywords