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Published in 2024 at "Communications Biology"
DOI: 10.1038/s42003-024-06159-9
Abstract: Cytosolic Ca2+ and Na+ allosterically regulate Na+/Ca2+ exchanger (NCX) proteins to vary the NCX-mediated Ca2+ entry/exit rates in diverse cell types. To resolve the structure-based dynamic mechanisms underlying the ion-dependent allosteric regulation in mammalian NCXs,…
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Keywords:
interactions full;
structural dynamics;
dynamics ca2;
ca2 interactions ... See more keywords