Mitochondrial regulation of [Ca2+]i oscillations during cell cycle resumption of the second meiosis of oocyte
Sign Up to like & getrecommendations! Published in 2018 at "Cell Cycle"
DOI: 10.1080/15384101.2018.1489179
Abstract: ABSTRACT Oocyte is arrested at metaphase of the second meiosis until fertilization switching on [Ca2+]i oscillations. Oocyte activation inefficiency is the most challenging problem for failed fertilization and embryonic development. Mitochondrial function and intracellular [Ca2+]i… read more here.
Keywords: mitochondrial function; second meiosis; ca2; ca2 oscillations ... See more keywords
Age-related alterations in fertilization-induced Ca2+ oscillations depend on the genetic background of mouse oocytes†
Sign Up to like & getrecommendations! Published in 2020 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioaa139
Abstract: Abstract Maternal aging affects various aspects of oocytes' physiology, including the functionality of their nuclear apparatus and mitochondria. In the present paper, we wished to investigate whether advanced reproductive age impacts oocytes' ability to generate… read more here.
Keywords: fertilization; maternal aging; age; genetic background ... See more keywords
Calcium oscillations in fertilized pig oocytes are associated with repetitive interactions between STIM1 and ORAI1†
Sign Up to like & getrecommendations! Published in 2018 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioy016
Abstract: ABSTRACT The Ca2+ entry mechanism that sustains the Ca2+ oscillations in fertilized pig oocytes was investigated. Stromal interaction molecule 1 (STIM1) and ORAI1 proteins tagged with various fluorophores were expressed in the oocytes. In some… read more here.
Keywords: oscillations fertilized; stim1; stim1 orai1; ca2 ... See more keywords
The role of ATP in the differential ability of Sr2+ to trigger Ca2+ oscillations in mouse and human eggs
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DOI: 10.1093/molehr/gaaa086
Abstract: Abstract At fertilization in mice and humans, the activation of the egg is caused by a series of repetitive Ca2+ oscillations which are initiated by phospholipase-C(zeta)ζ that generates inositol-1,4,5-trisphophate (InsP3). Ca2+ oscillations and egg activation… read more here.
Keywords: mouse eggs; human eggs; ca2 oscillations; sr2 ... See more keywords
β3‐adrenoceptor agonists inhibit carbachol‐evoked Ca2+ oscillations in murine detrusor myocytes
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DOI: 10.1111/bju.14090
Abstract: To test if carbachol (CCh)‐evoked Ca2+ oscillations in freshly isolated murine detrusor myocytes are affected by β3‐adrenoceptor (β‐AR) modulators. read more here.
Keywords: evoked ca2; carbachol; murine detrusor; ca2 oscillations ... See more keywords
Studies on the Mechanism of Lactate-Induced Increase in Ca2+ Oscillations in Carotid Body Type 1 Cells
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5719043
Abstract: Blood lactate concentration under normal conditions is ~1 mM and increases during hypoxia and exercise due to elevated anaerobic metabolism. Recent studies suggest that lactate acts directly on carotid body Type 1 chemoreceptor (CB) cells… read more here.
Keywords: physiology; increase ca2; mechanism lactate; ca2 oscillations ... See more keywords
ATP is an essential autocrine factor for pancreatic β‐cell signaling and insulin secretion
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DOI: 10.14814/phy2.15159
Abstract: ATP has been previously identified as an autocrine signaling factor that is co‐released with insulin to modulate and propagate β‐cell activity within islets of Langerhans. Here, we show that β‐cell activity and insulin secretion essentially… read more here.
Keywords: ca2 oscillations; cell; extracellular atp; insulin secretion ... See more keywords
KChIP3 coupled to Ca2+ oscillations exerts a tonic brake on baseline mucin release in the colon
Sign Up to like & getrecommendations! Published in 2018 at "eLife"
DOI: 10.7554/elife.39729
Abstract: Regulated mucin secretion from specialized goblet cells by exogenous agonist-dependent (stimulated) and -independent (baseline) manner is essential for the function of the epithelial lining. Over extended periods, baseline release of mucin can exceed quantities released… read more here.
Keywords: secretion; baseline mucin; baseline; ca2 oscillations ... See more keywords