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   Articles with "ca2 overload" as a keyword



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A Calcium Fluoride Nanozyme for Ultrasound‐Amplified and Ca2+‐Overload‐Enhanced Catalytic Tumor Nanotherapy

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recommendations! Published in 2022 at "Advanced Materials"

DOI: 10.1002/adma.202205680

Abstract: The anticancer mechanism of nanozymes is dominantly associated with the capacity for generation of reactive oxygen species (ROS) caused by the valence change of metal elements. However, very little research is focused on and has… read more here.

Keywords: calcium; ca2 overload; calcium fluoride; tumor ... See more keywords
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TDCPP protects cardiomyocytes from hypoxia‐reoxygenation injury induced apoptosis through mitigating calcium overload and promotion GSK‐3&bgr; phosphorylation

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recommendations! Published in 2018 at "Regulatory Toxicology and Pharmacology"

DOI: 10.1016/j.yrtph.2017.11.005

Abstract: ABSTRACT TDCPP, Tris (1, 3‐dichloro‐2‐propyl) phosphate belongs to a group of chemicals known as triester organophosphate flame retardants, It can alter calcium homeostasis at much lower concentrations in normal conditions, but the mechanism is unclear… read more here.

Keywords: tdcpp; bgr phosphorylation; ca2 overload; calcium ... See more keywords
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Mechanism of Stat1 in the neuronal Ca2+ overload after intracerebral hemorrhage via the H3K27ac/Trpm7 axis.

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recommendations! Published in 2022 at "Journal of neurophysiology"

DOI: 10.1152/jn.00083.2022

Abstract: Intracerebral hemorrhage (ICH) is classified as a subtype of stroke and Calcium (Ca2+) overload is a catalyst for ICH. This study explored the mechanisms of Stat1 (signal transducer and activator of transcription 1) in the… read more here.

Keywords: neuronal ca2; trpm7; h3k27ac; ca2 overload ... See more keywords
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Lercanidipine Synergistically Enhances Bortezomib Cytotoxicity in Cancer Cells via Enhanced Endoplasmic Reticulum Stress and Mitochondrial Ca2+ Overload

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recommendations! Published in 2019 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms20246112

Abstract: The proteasome inhibitor (PI), bortezomib (Btz), is effective in treating multiple myeloma and mantle cell lymphoma, but not solid tumors. In this study, we show for the first time that lercanidipine (Ler), an antihypertensive drug,… read more here.

Keywords: endoplasmic reticulum; ca2 overload; cancer cells; cells via ... See more keywords