Preconditioning by Levosimendan is Mediated by Activation of Mitochondrial Ca2+-Sensitive Potassium (mBKCa) Channels
Sign Up to like & getrecommendations! Published in 2018 at "Cardiovascular Drugs and Therapy"
DOI: 10.1007/s10557-018-6819-5
Abstract: PurposeActivation of mitochondrial large-conductance Ca2+-sensitive potassium (mBKCa)-channels is a crucial step for cardioprotection by preconditioning. Whether activation of these channels is involved in levosimendan-induced preconditioning is unknown. We investigated if cardioprotection by levosimendan requires activation… read more here.
Keywords: levosimendan; sensitive potassium; mbkca channels; mbkca ... See more keywords
Ca2+-Sensitive Potassium Channels
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28020885
Abstract: The Ca2+ ion is used ubiquitously as an intracellular signaling molecule due to its high external and low internal concentration. Many Ca2+-sensing ion channel proteins have evolved to receive and propagate Ca2+ signals. Among them… read more here.
Keywords: potassium channels; ca2 activated; ca2 sensitive; sensitive potassium ... See more keywords