A novel gain-of-function mutation in the ITPR1 suppressor domain causes spinocerebellar ataxia with altered Ca2+ signal patterns
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neurology"
DOI: 10.1007/s00415-017-8545-5
Abstract: We report three affected members, a mother and her two children, of a non-consanguineous Irish family who presented with a suspected autosomal dominant spinocerebellar ataxia characterized by early motor delay, poor coordination, gait ataxia, and… read more here.
Keywords: spinocerebellar ataxia; ca2 signal; function; itpr1 ... See more keywords
CRAC channels in secretory epithelial cell function and disease.
Sign Up to like & getrecommendations! Published in 2019 at "Cell calcium"
DOI: 10.1016/j.ceca.2018.12.010
Abstract: The receptor-evoked Ca2+ signal in secretory epithelia mediate many cellular functions essential for cell survival and their most fundamental functions of secretory granules exocytosis and fluid and electrolyte secretion. Ca2+ influx is a key component… read more here.
Keywords: receptor evoked; ca2 signal; crac; cell ... See more keywords
Epidemic-Like Calcium Signaling in Mobile Molecular Communication Networks
Sign Up to like & getrecommendations! Published in 2022 at "IEEE Transactions on NanoBioscience"
DOI: 10.1109/tnb.2022.3155644
Abstract: Molecular Communication is an emerging technology enabling communications in nano-networks. Ca2+ signal is one promising option of MC due to the important role in bio-metabolisms and the available characteristics in communication engineering. So far, scientists… read more here.
Keywords: calcium; ca2 signal; molecular communication; model ... See more keywords
Spatial and Temporal Calcium Signaling and Its Physiological Effects in Moso Bamboo under Drought Stress
Sign Up to like & getrecommendations! Published in 2019 at "Forests"
DOI: 10.3390/f10030224
Abstract: Elevations in cytosolic free calcium concentration constitute a fundamental signal transduction mechanism in plants; however, the particular characteristics of calcium ion (Ca2+) signal occurrence in plants is still under debate. Little is known about how… read more here.
Keywords: ca2; ca2 signal; calcium; drought stress ... See more keywords
A Central Role for TRPM4 in Ca2+-Signal Amplification and Vasoconstriction
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23031465
Abstract: Transient receptor potential melastatin-4 (TRPM4) is activated by an increase in intracellular Ca2+ concentration and is expressed on smooth muscle cells (SMCs). It is implicated in the myogenic constriction of cerebral arteries. We hypothesized that… read more here.
Keywords: vasoconstriction; signal amplification; trpm4; role ... See more keywords