Simulated Microgravity Conditions Modulate Ca2+ Transport through TRPV4 Channels
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.11.1371
Abstract: Astronauts in space tend to lose ten times as much bone mass each month as severe osteoporosis patients on Earth. Multiple reports on unloading-induced osteoporosis in bed-ridden patients indicate that bone mass correlates positively with… read more here.
Keywords: microgravity conditions; simulated microgravity; trpv4 channels; ca2 ... See more keywords
Elucidating the Uncoupling of ATP Hydrolysis and Ca2+ Transport in SERCA by Sarcolipin
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.11.2708
Abstract: The activity of the sarco(endo)plasmic reticulum Ca2+ -ATPase (SERCA), which plays a key role in muscle contraction and relaxation, is regulated by sarcolipin (SLN), a 31-residue transmembrane peptide. Sarcolipin has been shown to uncouple ATP… read more here.
Keywords: atp hydrolysis; serca; hydrolysis ca2; ca2 transport ... See more keywords
Mitochondrial Ca2+ Transport: Mechanisms, Molecular Structures, and Role in Cells
Sign Up to like & getrecommendations! Published in 2019 at "Biochemistry (Moscow)"
DOI: 10.1134/s0006297919060026
Abstract: Mitochondria are among the most important cell organelles involved in the regulation of intracellular calcium homeostasis. During the last decade, a number of molecular structures responsible for the mitochondrial calcium transport have been identified including… read more here.
Keywords: ca2 transport; role; transport; ca2 ... See more keywords
Developmental expression of mechano-stimulated Ca2+ transport pathways in kidney organoid tubules
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5732702
Abstract: Kidney organoids derived from human pluripotent stem cells exhibit glomerular- and tubular-like structures. As the technology for culturing organoids advances, the goal of promoting terminal differentiation demands that priority be given to characterization of their… read more here.
Keywords: increase; expression; ca2 transport; physiology ... See more keywords
Ultrasensitive Diamond Microelectrode Application in the Detection of Ca2+ Transport by AnnexinA5-Containing Nanostructured Liposomes
Sign Up to like & getrecommendations! Published in 2022 at "Biosensors"
DOI: 10.3390/bios12070525
Abstract: This report describes the innovative application of high sensitivity Boron-doped nanocrystalline diamond microelectrodes for tracking small changes in Ca2+ concentration due to binding to Annexin-A5 inserted into the lipid bilayer of liposomes (proteoliposomes), which could… read more here.
Keywords: application; ca2 transport; transport; ultrasensitive diamond ... See more keywords
A Review of the Role of Endo/Sarcoplasmic Reticulum-Mitochondria Ca2+ Transport in Diseases and Skeletal Muscle Function
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Environmental Research and Public Health"
DOI: 10.3390/ijerph18083874
Abstract: The physical contact site between a mitochondrion and endoplasmic reticulum (ER), named the mitochondria-associated membrane (MAM), has emerged as a fundamental platform for regulating the functions of the two organelles and several cellular processes. This… read more here.
Keywords: skeletal muscle; reticulum; muscle; muscle function ... See more keywords
Mechanism of Ca2+ transport by ferroportin
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.7554/elife.82947
Abstract: Ferroportin (Fpn) is a transporter that releases Fe2+ from cells and is important for iron homeostasis in circulation. Export of Fe2+ by Fpn is coupled to import of H+ to maintain charge balance. Although Ca2+… read more here.
Keywords: ferroportin; fpn; ca2 transport; transport ... See more keywords