Disruption of entire Cables2 locus leads to embryonic lethality by diminished Rps21 gene expression and enhanced p53 pathway
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DOI: 10.7554/elife.50346
Abstract: In vivo function of CDK5 and Abl enzyme substrate 2 (Cables2), belonging to the Cables protein family, is unknown. Here, we found that targeted disruption of the entire Cables2 locus (Cables2d) caused growth retardation and… read more here.
Keywords: disruption; cables2; embryonic lethality; cables2 locus ... See more keywords