Assessment of cabozantinib treatment on QT interval in a phase 3 study in medullary thyroid cancer: evaluation of indirect QT effects mediated through treatment-induced changes in serum electrolytes
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Chemotherapy and Pharmacology"
DOI: 10.1007/s00280-017-3349-y
Abstract: PurposeThis study evaluated factors impacting QTc interval in a phase 3 trial of cabozantinib in progressive, metastatic, medullary thyroid cancer (MTC).MethodsElectrocardiogram (12-lead ECG) measurements were obtained at screening, and at pre-dose, and 2, 4, and… read more here.
Keywords: phase; treatment; cabozantinib treatment; study ... See more keywords
Clinical Utility of Cabozantinib in the Treatment of Locally Advanced or Metastatic Differentiated Thyroid Carcinoma: Patient Selection and Reported Outcomes
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Management and Research"
DOI: 10.2147/cmar.s348711
Abstract: Abstract Treatment of differentiated thyroid cancer (DTC) is multidisciplinary and begins with surgical intervention. Often, radioactive iodine is used as the prototype targeted therapy to ablate any residual thyroid tissue or metastatic deposits. While these… read more here.
Keywords: cabozantinib treatment; differentiated thyroid; utility cabozantinib; treatment locally ... See more keywords