Feeding of carob (Ceratonia siliqua) to sheep infected with gastrointestinal nematodes reduces faecal egg counts and worm fecundity.
Sign Up to like & getrecommendations! Published in 2020 at "Veterinary parasitology"
DOI: 10.1016/j.vetpar.2020.109200
Abstract: The present study explored the anthelmintic effects of condensed tannins (CT) in carob (Ceratonia siliqua) pods fed to sheep against gastrointestinal nematodes. Three independent in vivo trials tested whether i) carob pod (CaBP)-containing feed had… read more here.
Keywords: worm fecundity; fecundity; effect; carob ... See more keywords
17β-estradiol binding to ERα promotes the progression of prolactinoma through estrogen-response element-induced CaBP-9k up-regulation
Sign Up to like & getrecommendations! Published in 2020 at "Bioscience Reports"
DOI: 10.1042/bsr20191330
Abstract: Abstract 17β-estradiol (E2) is considered to be an important instigator of prolactinoma, and can positively regulate the expression of calbindin-D9k (CaBP-9k) which contains an estrogen responsive element (ERE) via estrogen receptors (ERs). However, the detailed… read more here.
Keywords: progression; induced cabp; cabp regulation; cell ... See more keywords
Cardiac Safety of Omadacycline in the IV/oral Phase 3 Acute Bacterial Skin and Skin Structure Infection (ABSSSI) and in the IV/oral Phase 3 Community-acquired Bacterial Pneumonia (CABP) Studies
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DOI: 10.1093/ofid/ofx163.1416
Abstract: ACKNOWLEDGMENTS REFERENCES • Omadacycline (OMC) is the first aminomethylcycline in late-stage clinical development – Aminomethylcyclines are semisynthetic antibiotics related to the tetracyclines that overcome the 2 main mechanisms of tetracycline resistance, efflux pumps and ribosomal… read more here.
Keywords: phase; oral phase; skin; community acquired ... See more keywords
1365. In Vitro Activity of Lefamulin (LEF) Against Bacterial Pathogens Causing Community-Acquired Bacterial Pneumonia (CABP): SENTRY Surveillance 2016 Results From Asia-Pacific (APAC) and Latin America (LA)
Sign Up to like & getrecommendations! Published in 2018 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofy210.1196
Abstract: Abstract Background LEF, a novel pleuromutilin antibiotic for IV and oral use, recently completed a phase 3 trial for the treatment of CABP in adults where it demonstrated noninferiority to moxifloxacin ± linezolid. LEF selectively… read more here.
Keywords: shareholder; lef; vitro activity; cabp ... See more keywords
703. In Vitro Activity of Lefamulin Against Bacterial Pathogens Causing Community-Acquired Bacterial Pneumonia (CABP): SENTRY Surveillance 2017–2018 Results From the United States (US)
Sign Up to like & getrecommendations! Published in 2019 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofz360.771
Abstract: Abstract Background Lefamulin (LEF), a novel pleuromutilin protein synthesis inhibitor in development for use as an empiric IV and oral monotherapy for CABP, recently demonstrated safety and efficacy in two phase 3 trials in adults… read more here.
Keywords: oral days; vitro activity; activity; united states ... See more keywords
Reducing the use of empiric antibiotic therapy in COVID-19 on hospital admission
Sign Up to like & getrecommendations! Published in 2021 at "BMC Infectious Diseases"
DOI: 10.1186/s12879-021-06219-z
Abstract: Background Empiric antibiotics for community acquired bacterial pneumonia (CABP) are often prescribed to patients with COVID-19, despite a low reported incidence of co-infections. Stewardship interventions targeted at facilitating appropriate antibiotic prescribing for CABP among COVID-19… read more here.
Keywords: intervention; guideline; antibiotic therapy; covid ... See more keywords