The HIF-prolyl hydroxylases have distinct and nonredundant roles in colitis-associated cancer
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DOI: 10.1172/jci.insight.153337
Abstract: Colitis-associated colorectal cancer (CAC) is a severe complication of inflammatory bowel disease (IBD). HIF-prolyl hydroxylases (PHD1, PHD2, and PHD3) control cellular adaptation to hypoxia and are considered promising therapeutic targets in IBD. However, their relevance… read more here.
Keywords: colitis associated; cac growth; hif prolyl; cac ... See more keywords