The differential effects of sarcopenia and cachexia on overall survival for pancreatic ductal adenocarcinoma patients following pancreatectomy: A retrospective study based on a large population
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Medicine"
DOI: 10.1002/cam4.5779
Abstract: Both cachexia and sarcopenia have been considered adverse predictors for prognosis in patients with pancreatic cancer; although sarcopenia and cachexia share some similarities, they are still defined as distinct nutritional conditions. We aimed to explore… read more here.
Keywords: patients following; ductal adenocarcinoma; pancreatic ductal; cachexia ... See more keywords
Development of skeletal muscle fibrosis in a rodent model of cancer cachexia.
Sign Up to like & getrecommendations! Published in 2023 at "Cell biochemistry and function"
DOI: 10.1002/cbf.3797
Abstract: Cachexia is characterized by losses in lean body mass and its progression results in worsened quality of life and exacerbated outcomes in cancer patients. However, the role and impact of fibrosis during the early stages… read more here.
Keywords: tumor; development; skeletal muscle; mice ... See more keywords
RANKL Blockade Reduces Cachexia and Bone Loss Induced by Non‐Metastatic Ovarian Cancer in Mice
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.4480
Abstract: Tumor‐ and bone‐derived soluble factors have been proposed to participate in the alterations of skeletal muscle size and function in cachexia. We previously showed that mice bearing ovarian cancer (OvCa) exhibit cachexia associated with marked… read more here.
Keywords: bone; rankl; muscle; cachexia ... See more keywords
Bioelectrical impedance analysis for diagnosing sarcopenia and cachexia: what are we really estimating?
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.12159
Abstract: As reference methods are not available for identifying low skeletal muscle mass in clinical practice, the European Group on Sarcopenia in Older People the Asian Working Group for Sarcopenia and the International Consensus for Cancer… read more here.
Keywords: sarcopenia; skeletal muscle; cachexia; muscle ... See more keywords
Megestrol acetate for cachexia–anorexia syndrome. A systematic review
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.12292
Abstract: In 1993, megestrol acetate (MA) was approved by the US Food and Drug Administration for the treatment of anorexia, cachexia, or unexplained weight loss in patients with acquired immunodeficiency syndrome. The mechanism by which MA… read more here.
Keywords: megestrol acetate; systematic review; cachexia; adverse events ... See more keywords
Prevalence of rheumatoid cachexia in rheumatoid arthritis: a systematic review and meta‐analysis
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.12320
Abstract: Low muscle mass occurs in patients with rheumatoid arthritis without weight loss; this condition is referred as rheumatoid cachexia. The aim of the current study was to perform a systematic review with meta‐analysis to determine… read more here.
Keywords: cachexia; review meta; rheumatoid; rheumatoid cachexia ... See more keywords
Cachexia as a common characteristic in multiple chronic disease
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.12388
Abstract: Cachexia, or body wasting, is a serious complication and frequently occurs at advanced stage of the variety of chronic diseases, including cancer, multiple inflammatory organ-specific disease, and cardiovascular disease. Cachexia affects the life quality and… read more here.
Keywords: cachexia; muscle; disease; muscle tissue ... See more keywords
The prognostic significance of weight loss in chronic obstructive pulmonary disease‐related cachexia: a prospective cohort study
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.12463
Abstract: Cachexia is an important extra‐pulmonary manifestation of chronic obstructive pulmonary disease (COPD) presenting as unintentional weight loss and altered body composition. Previous studies have focused on the relative importance of body composition compared with body… read more here.
Keywords: chronic obstructive; cachexia; obstructive pulmonary; weight loss ... See more keywords
MT‐102 prevents tissue wasting and improves survival in a rat model of severe cancer cachexia
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.12537
Abstract: Cachexia, a common manifestation of malignant cancer, is associated with wasting of skeletal muscle and fat tissue. In this study, we investigated the effects of a new first in class anabolic catabolic transforming agent on… read more here.
Keywords: cachexia; tissue; cancer cachexia; cancer ... See more keywords
Dysregulation of epicardial adipose tissue in cachexia due to heart failure: the role of natriuretic peptides and cardiolipin
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.12631
Abstract: Cachexia worsens long‐term prognosis of patients with heart failure (HF). Effective treatment of cachexia is missing. We seek to characterize mechanisms of cachexia in adipose tissue, which could serve as novel targets for the treatment. read more here.
Keywords: adipose tissue; cachexia; heart failure;
Biomarkers for cancer cachexia: where do we stand?
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.12641
Abstract: Cancer cachexia has been recognized as a major, life‐limiting complication in the treatment of cancer patients and is composed of distinctive stages: pre‐cachexia, cachexia, and refractory cachexia. An early diagnosis of cachexia, possibly in the… read more here.
Keywords: cachexia stand; biomarkers cancer; cachexia; cancer cachexia ... See more keywords