Titanium dioxide nanoparticles translocate through differentiated Caco‐2 cell monolayers, without disrupting the barrier functionality or inducing genotoxic damage
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.3630
Abstract: The widespread use of titanium dioxide nanoparticles (TiO2NPs) in commercial food products makes intestinal cells a suitable target. Accordingly, we have used the human colon adenocarcinoma Caco‐2 cells to detect their potential harmful effects. Caco‐2… read more here.
Keywords: microscopy; cell monolayers; titanium dioxide; dioxide nanoparticles ... See more keywords
Calcium fructoborate regulate colon cancer (Caco‐2) cytotoxicity through modulation of apoptosis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23021
Abstract: Sugar‐borate esters have recently been reported to have anti‐cancer potential. Among the sugar‐borate esters, calcium fructoborate (CaFB) possesses beneficial effects on human health. Despite the beneficial effects of CaFB, there is a lack of knowledge… read more here.
Keywords: cancer; apoptosis; calcium fructoborate; colon cancer ... See more keywords
Absorption of iron from Tegillarca granosa using an in vitro simulated digestion and Caco-2/HepG2 co-culture system.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.12200
Abstract: BACKGROUND Iron deficiency anemia (IDA) is one severe micronutrient malnutrition and has captured worldwide attention. This study evaluated the in vitro iron absorption of two iron-binding proteins (hemoglobin and ferritin) from Tegillarca granosa (T. granosa).… read more here.
Keywords: hemoglobin ferritin; iron; granosa; iron absorption ... See more keywords
Different mitochondrial response to cisplatin and hyperthermia treatment in human AGS, Caco-2 and T3M4 cancer cell lines
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Bioenergetics and Biomembranes"
DOI: 10.1007/s10863-018-9764-x
Abstract: Gastrointestinal cancers (gastric, pancreatic and colorectal) are life-threatening diseases, which easily spread to peritoneal cavity (Juhl et al. in Int J Cancer 57:330–335, 1994; Schneider et al. in Gastroenterology 128:1606–1625, 2005; Geer and Brennan in… read more here.
Keywords: cisplatin hyperthermia; cisplatin; t3m4 cancer; cancer ... See more keywords
Diamine Oxidase from White Pea (Lathyrus sativus) Combined with Catalase Protects the Human Intestinal Caco-2 Cell Line from Histamine Damage
Sign Up to like & getrecommendations! Published in 2017 at "Applied Biochemistry and Biotechnology"
DOI: 10.1007/s12010-016-2390-3
Abstract: Diamine oxidase (DAO) administration has been proposed to treat certain gastrointestinal dysfunctions induced by histamine, an immunomodulator, signaling, and pro-inflammatory factor. However, H2O2 resulting from the oxidative deamination of histamine by DAO may be toxic.… read more here.
Keywords: white pea; histamine; dao; pea lathyrus ... See more keywords
LC-MS proteomic profiling of Caco-2 human intestinal cells exposed to the copper-chelating agent, triethylenetetramine: A preliminary study.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.01.138
Abstract: Homeostasis of metal micronutrients such as copper is tightly regulated to ensure deficiency does not occur while restricting damage resulting from excess accumulation. Using LC-MS the effect on the proteome of intestinal Caco-2 cells of exposure… read more here.
Keywords: copper; study; intestinal cells; proteomic profiling ... See more keywords
Development of Caco-2 cells co-expressing CYP3A4 and NADPH-cytochrome P450 reductase using a human artificial chromosome for the prediction of intestinal extraction ratio of CYP3A4 substrates.
Sign Up to like & getrecommendations! Published in 2017 at "Drug metabolism and pharmacokinetics"
DOI: 10.1016/j.dmpk.2016.08.004
Abstract: The Caco-2 cells co-expressing cytochrome P450 (CYP) 3A4 and NADPH-cytochrome P450 reductase (CPR) were developed using a human artificial chromosome (HAC) vector. The CYP3A4 and CPR genes were cloned into the HAC vector in CHO cells… read more here.
Keywords: hac; caco cells; cyp3a4; cyp3a4 cpr ... See more keywords
Assessment of the in vitro anticancer activities of cyanobacteria mediated silver oxide and gold nanoparticles in human colon CaCo-2 and cervical HeLa cells
Sign Up to like & getrecommendations! Published in 2021 at "Environmental Nanotechnology, Monitoring and Management"
DOI: 10.1016/j.enmm.2021.100556
Abstract: Abstract This work aims to assess the cytotoxicity of silver oxide and gold nanoparticles on two cancer cell cultures, human colon CaCo-2, and cervical HeLa cancer cells. Silver oxide and gold nanoparticles were synthesized using… read more here.
Keywords: oxide gold; silver oxide; gold nanoparticles; cancer ... See more keywords
In vitro anticancer activity of fucoidan extracted from Sargassum cinereum against Caco-2 cells.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2019.07.127
Abstract: Fucoidan is a marine sulfated polysaccharide, which is extracted from brown seaweed that has a wide range of bioactivities including anti-cancer properties. However, the underlying mechanism of fucoidan on its anti-cancer and apoptotic activity against… read more here.
Keywords: caco cells; fucoidan; anti cancer; activity ... See more keywords
Comparing the sensitivity of different intestinal Caco-2 in vitro monocultures and co-cultures to amorphous silicon dioxide nanomaterials and the clay montmorillonite
Sign Up to like & getrecommendations! Published in 2019 at "NanoImpact"
DOI: 10.1016/j.impact.2019.100165
Abstract: Abstract A range of in vitro models of the gastro-intestinal tract have been developed that vary in their composition and complexity. Such models could be useful for assessing the hazard of ingested nanomaterials (NMs). This… read more here.
Keywords: clay montmorillonite; vitro models; sio2 nms; caco ... See more keywords
Anti-inflammatory effect of polyphenols from Chilean currants (Ribes magellanicum and R. punctatum) after in vitro gastrointestinal digestion on Caco-2 cells
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2019.06.007
Abstract: Abstract The polyphenol-enriched extracts (PEEs) of Chilean currants Ribes magellanicum and R. punctatum were submitted to in vitro gastro-intestinal digestion and their anti-inflammatory activities were assessed using differentiated human Caco-2 (clone C2BBe1) cells stimulated with… read more here.
Keywords: currants ribes; chilean currants; caco; punctatum ... See more keywords