Correlation between copper speciation and transport pathway in Caco-2 cells.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.12292
Abstract: BACKGROUND Previous studies have demonstrated that in contrast to the properties of food-derived copper, water-derived copper exerts neurotoxic effects and exhibits different speciation during digestion. The cellular uptake efficiencies of different speciation of copper are… read more here.
Keywords: derived copper; copper; caco cells; accumulation ... See more keywords
Partially hydrolyzed guar gum upregulates heat shock protein 27 in intestinal Caco-2 cells and mouse intestine via mTOR and ERK signaling.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.12551
Abstract: BACKGROUND The intestinal epithelium acts as a barrier against harmful luminal materials, thus, preventing intestinal diseases, and maintaining intestinal health. Heat shock protein 27 (HSP27) promotes intestinal epithelial integrity under physiological and stressed conditions. The… read more here.
Keywords: hsp27 expression; caco cells; phgg; intestinal caco ... See more keywords
Effects of polystyrene microbeads on cytotoxicity and transcriptomic profiles in human Caco‐2 cells
Sign Up to like & getrecommendations! Published in 2019 at "Environmental Toxicology"
DOI: 10.1002/tox.22885
Abstract: Microplastics (MPs) pollution is a global paradigm that raises concern in relation to environment and human health. In order to investigate the molecular toxicity mechanisms of MPs, transcriptomic analyses were performed on in vitro Caco‐2… read more here.
Keywords: caco cells; microbeads cytotoxicity; polystyrene microbeads; transcriptomic profiles ... See more keywords
Adiponectin administration alleviates DSS-induced colonic inflammation in Caco-2 cells and mice
Sign Up to like & getrecommendations! Published in 2018 at "Inflammation Research"
DOI: 10.1007/s00011-018-1155-6
Abstract: BackgroundAdiponectin, a protein hormone produced by adipose tissues, exhibits anti-inflammatory functions in various models. This study was investigated the effects of adiponectin on dextran sodium sulfate (DSS)-colonic injury, inflammation, apoptosis, and intestinal barrier dysfunction in… read more here.
Keywords: colonic inflammation; caco cells; dss induced; induced colonic ... See more keywords
Blackcurrant anthocyanins stimulated cholesterol transport via post-transcriptional induction of LDL receptor in Caco-2 cells
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Nutrition"
DOI: 10.1007/s00394-017-1506-z
Abstract: PurposesWe previously showed that polyphenol-rich blackcurrant extract (BCE) showed a hypocholesterolemic effect in mice fed a high fat diet. As direct cholesterol removal from the body via the intestine has been recently appreciated, we investigated… read more here.
Keywords: bce; caco cells; transport; cholesterol ... See more keywords
Lactobacillus spp. impair the ability of Listeria monocytogenes FBUNT to adhere to and invade Caco-2 cells
Sign Up to like & getrecommendations! Published in 2018 at "Biotechnology Letters"
DOI: 10.1007/s10529-018-2572-x
Abstract: ObjectivesThe objective of this study was to evaluate the ability of Lactobacillus curvatus CRL705, CRL1532, and CRL1533 and Lactobacillus sakei CRL1613 to survive under simulated gastrointestinal conditions. Moreover, a microencapsulation approach was proposed to improve… read more here.
Keywords: monocytogenes fbunt; ability listeria; caco cells; lactobacillus spp ... See more keywords
The presence of palmitate affected the colloidal stability of ZnO NPs but not the toxicity to Caco-2 cells
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Nanoparticle Research"
DOI: 10.1007/s11051-017-4038-9
Abstract: Nanoparticles (NPs) are finding increasing use in food science, but the toxicity of NPs following oral exposure is not fully known. When present in food and food-related products, food components may interact with NPs and… read more here.
Keywords: caco cells; presence; zno nps; zno ... See more keywords
Cellular mechanism for herbal medicine Junchoto to facilitate intestinal Cl−/water secretion that involves cAMP-dependent activation of CFTR
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Natural Medicines"
DOI: 10.1007/s11418-018-1207-9
Abstract: Constipation is a common symptom frequently compromising the quality of daily life. Several mechanistically different drugs have been used to mitigate constipation, including Japanese herbal (Kampo) medicines. However, the mechanisms of their actions are often… read more here.
Keywords: medicine; water secretion; caco cells; activation cftr ... See more keywords
Agaricus bisporus peptide fractions confer cytoprotective ability against hydrogen peroxide-induced oxidative stress in HepG2 and Caco-2 cells
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Food Measurement and Characterization"
DOI: 10.1007/s11694-020-00497-y
Abstract: This study aimed at isolating and identifying antioxidative peptides from Agaricus bisporus protein hydrolysate ultrafiltration fraction. Pancreatin was used to hydrolyze A. bisporus protein isolate and ultrafiltration was used to obtain 1–3 kDa fraction. Through… read more here.
Keywords: caco cells; hepg2 caco; stress; peptide fractions ... See more keywords
Zinc induces iron egress from intestinal Caco-2 cells via induction of Hephaestin: A role for PI3K in intestinal iron absorption.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.01.023
Abstract: In previous studies we demonstrated that zinc stimulates iron uptake in intestinal Caco-2 cells via Zinc-PI3K-IRP2-DMT1 axis. In the current study we investigated the effect of zinc on basolateral iron release and characterized the associated mechanisms.… read more here.
Keywords: caco cells; zinc; heph; expression ... See more keywords
Dynamics of absorption, metabolism, and excretion of 5-aminolevulinic acid in human intestinal Caco-2 cells
Sign Up to like & getrecommendations! Published in 2017 at "Biochemistry and Biophysics Reports"
DOI: 10.1016/j.bbrep.2017.07.006
Abstract: 5-Aminolevulinic acid (ALA) is a precursor for the biosynthesis of porphyrins and heme. Although the oral administration of ALA has been widely applied in clinical settings, the dynamics of its absorption, metabolism, and excretion within… read more here.
Keywords: aminolevulinic acid; ala; caco cells; absorption metabolism ... See more keywords