Notch3 protein expression in skin fibroblasts from CADASIL patients
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the Neurological Sciences"
DOI: 10.1016/j.jns.2018.04.027
Abstract: AIM CADASIL is an inherited cerebrovascular disease caused by mutations in the NOTCH3 gene. Notch signaling is involved in a broad spectrum of function, from the cell proliferation to apoptosis. Thus far, because the molecular… read more here.
Keywords: protein expression; cadasil patients; notch3 protein; expression ... See more keywords
Reduced Venous Oxygen Saturation Associates With Increased Dependence of Patients With Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy: A 7.0-T Magnetic Resonance Imaging Study.
Sign Up to like & getrecommendations! Published in 2019 at "Stroke"
DOI: 10.1161/strokeaha.119.026376
Abstract: Background and Purpose- Accumulating evidence has de monstrated hemodynamic abnormalities and cerebral hypoperfusion in patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). Increased venous susceptibility assessed by susceptibility weighted imaging and… read more here.
Keywords: venous oxygen; venous susceptibility; susceptibility; oxygen saturation ... See more keywords
Plasma neurofilament light chain and glial fibrillary acidic protein predict stroke in CADASIL
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Neuroinflammation"
DOI: 10.1186/s12974-020-01813-5
Abstract: Background Stroke remains the most cumbersome disease burden in patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). This study aimed to investigate whether plasma biomarkers can reflect disease severity and predict… read more here.
Keywords: neurofilament light; cadasil; cadasil patients; predict stroke ... See more keywords
Effects of Cerebral Blood Flow and White Matter Integrity on Cognition in CADASIL Patients
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2018.00741
Abstract: Background: It remains unclear whether the degree of white matter tract damage or cerebral hypoperfusion can better predict global cognitive impairment in CADASIL. We sought to determine the independent effects of cerebral perfusion status and… read more here.
Keywords: wmh; matter; cadasil patients; global cognitive ... See more keywords