The Coupled Atomistic/Discrete-Dislocation method in 3d part I: Concept and algorithms
Sign Up to like & getrecommendations! Published in 2018 at "Journal of The Mechanics and Physics of Solids"
DOI: 10.1016/j.jmps.2018.05.004
Abstract: Abstract The Coupled Atomistic/Discrete-Dislocation (CADD) method is a concurrent multiscale technique that couples atomistic and discrete dislocation domains with the ability to pass dislocations seamlessly between domains. CADD has been demonstrated only in 2d plane-strain… read more here.
Keywords: cadd; dislocation; coupled atomistic; method ... See more keywords
CADD: predicting the deleteriousness of variants throughout the human genome
Sign Up to like & getrecommendations! Published in 2019 at "Nucleic Acids Research"
DOI: 10.1093/nar/gky1016
Abstract: Abstract Combined Annotation-Dependent Depletion (CADD) is a widely used measure of variant deleteriousness that can effectively prioritize causal variants in genetic analyses, particularly highly penetrant contributors to severe Mendelian disorders. CADD is an integrative annotation… read more here.
Keywords: cadd predicting; cadd; human genome; predicting deleteriousness ... See more keywords
S14.5 (Oral Abstract Presentation): Sweet relief for preeclampsia: Targeting autophagy and proteinopathy
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Reproductive Immunology"
DOI: 10.1111/aji.71_13546
Abstract: 65 blood pressurewasmeasured, fetal weight was recorded, and placenta was collected and subjected to immunostaining and RNA sequencing. The kidney was fixed and processed for HE staining for glomerular endotheliosis. Results: A class of disaccharides… read more here.
Keywords: university; colonization; gbs; transmission ... See more keywords
Computer-Aided Drug Design (CADD) to De-Orphanize Marine Molecules: Finding Potential Therapeutic Agents for Neurodegenerative and Cardiovascular Diseases
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DOI: 10.3390/md20010053
Abstract: Computer-aided drug design (CADD) techniques allow the identification of compounds capable of modulating protein functions in pathogenesis-related pathways, which is a promising line on drug discovery. Marine natural products (MNPs) are considered a rich source… read more here.
Keywords: aided drug; drug design; cadd; design ... See more keywords