Associations between genetic variants of KIF5B, FMN1, and MGAT3 in the cadherin pathway and pancreatic cancer risk
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Medicine"
DOI: 10.1002/cam4.3603
Abstract: Because the cadherin‐mediated signaling pathway promotes cancer progression, we assessed associations between genetic variants in 109 cadherin‐related genes and risk of pancreatic cancer (PanC) by using genotyping data from publically available genome‐wide association studies (GWAS)… read more here.
Keywords: risk; associations genetic; genetic variants; pancreatic cancer ... See more keywords
Cadherin interplay during neural crest segregation from the non‐neural ectoderm and neural tube in the early chick embryo
Sign Up to like & getrecommendations! Published in 2017 at "Developmental Dynamics"
DOI: 10.1002/dvdy.24517
Abstract: Background: In the avian embryo, neural crest (NC) progenitors arise in the neuroectoderm during gastrulation, long before their dissemination. Although the gene regulatory network involved in NC specification has been deciphered, the mechanisms involved in… read more here.
Keywords: cadherin; epidermis neural; neural tube; embryo ... See more keywords
ALDOLASE A regulates invasion of bladder cancer cells via E‐cadherin‐EGFR signaling
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28642
Abstract: Glycolysis and glycogenesis are known to be tightly associated with cancer cell migration. However, their roles in bladder cancer have not been reported. In this study, ALDOLASE A (ALDOA) was identified in a coexpression network… read more here.
Keywords: bladder cancer; cancer cells; cancer; cell ... See more keywords
The expression of VE-cadherin in breast cancer cells modulates cell dynamics as a function of tumor differentiation and promotes tumor–endothelial cell interactions
Sign Up to like & getrecommendations! Published in 2017 at "Histochemistry and Cell Biology"
DOI: 10.1007/s00418-017-1619-8
Abstract: The cadherin switch has profound consequences on cancer invasion and metastasis. The endothelial-specific vascular endothelial cadherin (VE-cadherin) has been demonstrated in diverse cancer types including breast cancer and is supposed to modulate tumor progression and… read more here.
Keywords: breast cancer; expression; cell; cadherin ... See more keywords
Puerarin Protects Against LPS-Induced Vascular Endothelial Cell Hyperpermeability via Preventing Downregulation of Endothelial Cadherin
Sign Up to like & getrecommendations! Published in 2019 at "Inflammation"
DOI: 10.1007/s10753-019-01014-0
Abstract: In the present study, we aimed to investigate the effects of puerarin on the hyperpermeability of vascular endothelial cells induced by lipopolysaccharide (LPS) and its underlying mechanisms. Human umbilical vein endothelial cells (HUVECs) were pre-incubated… read more here.
Keywords: lps induced; puerarin; hyperpermeability; vascular endothelial ... See more keywords
miR-149-PARP-2 Signaling Regulates E-cadherin and N-cadherin Expression in the Murine Model of Endometrium Receptivity
Sign Up to like & getrecommendations! Published in 2021 at "Reproductive Sciences"
DOI: 10.1007/s43032-021-00710-3
Abstract: Cadherins play an essential role in the attachment of the blastocyst to the endometrium, a process known as endometrial receptivity. Loss of E-cadherin expression is essential during the process, while the expression level of the… read more here.
Keywords: cadherin expression; cadherin cadherin; receptivity; endometrial receptivity ... See more keywords
VE-cadherin functionalized injectable PAMAM/HA hydrogel promotes endothelial differentiation of hMSCs and vascularization
Sign Up to like & getrecommendations! Published in 2020 at "Applied Materials Today"
DOI: 10.1016/j.apmt.2020.100690
Abstract: Abstract The functionalization of hydrogels for tissue engineering mainly focuses on the modification of hydrogels with extracellular matrices (ECM) and growth factors to promote vascularization by bio-mimicking vascular extracellular microenvironment. However, the lack of cell-cell… read more here.
Keywords: hmscs; vascularization; hydrogel; cell ... See more keywords
C-mannosylated tryptophan-containing WSPW peptide binds to actinin-4 and alters E-cadherin subcellular localization in lung epithelial-like A549 cells.
Sign Up to like & getrecommendations! Published in 2021 at "Biochimie"
DOI: 10.1016/j.biochi.2021.10.007
Abstract: The Trp-x-x-Trp (W-x-x-W) peptide motif, a consensus site for C-mannosylation, is the functional motif in cytokine type I receptors or thrombospondin type I repeat (TSR) superfamily proteins. W-x-x-W motifs are important for physiological and pathological… read more here.
Keywords: a549 cells; wspw peptides; mannosylation; localization ... See more keywords
Integrin linked kinase regulates endosomal recycling of N-cadherin in melanoma cells.
Sign Up to like & getrecommendations! Published in 2020 at "Cellular signalling"
DOI: 10.1016/j.cellsig.2020.109642
Abstract: Malignant transformation is characterized by a phenotype "switch" from E- to N-cadherin - a major hallmark of epithelial to mesenchymal transition (EMT). The increased expression of N-cadherin is commonly followed by a growing capacity for… read more here.
Keywords: melanoma; integrin linked; ilk; expression ... See more keywords
Prognostic Role of N‐cadherin Expression in Patients With Invasive Bladder Cancer
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Genitourinary Cancer"
DOI: 10.1016/j.clgc.2017.07.001
Abstract: Background We assessed the role of N‐cadherin as a prognostic biomarker in patients with invasive bladder cancer (BCa) who had undergone radical cystectomy (RC). Patients and Methods The present retrospective single‐center study included 433 BCa… read more here.
Keywords: cadherin expression; patients invasive; expression; cancer ... See more keywords
Single-nucleotide polymorphisms of the adherent junction component cadherin gene are associated with leukoaraiosis.
Sign Up to like & getrecommendations! Published in 2018 at "Gene"
DOI: 10.1016/j.gene.2018.07.007
Abstract: BACKGROUND Leukoaraiosis (LA) is one of the manifestations of cerebral small vessel disease. Blood-brain barrier (BBB) disruption plays a key role in LA. Cadherin is a component of adherent junctions (AJ), which play a crucial… read more here.
Keywords: nucleotide polymorphisms; component cadherin; single nucleotide; cadherin gene ... See more keywords