Type-1 cytokines regulate matrix metalloprotease-9 production and E-cadherin disruption to promote melanocyte loss in vitiligo.
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DOI: 10.1172/jci.insight.133772
Abstract: Loss of melanocytes is the pathological hallmark of vitiligo, a chronic inflammatory skin depigmenting disorder induced by exaggerated immune response, including autoreactive CD8 T cells producing high levels of type-1 cytokines. However, the interplay between… read more here.
Keywords: type cytokines; vitiligo; disruption; skin ... See more keywords