miR-149-PARP-2 Signaling Regulates E-cadherin and N-cadherin Expression in the Murine Model of Endometrium Receptivity
Sign Up to like & getrecommendations! Published in 2021 at "Reproductive Sciences"
DOI: 10.1007/s43032-021-00710-3
Abstract: Cadherins play an essential role in the attachment of the blastocyst to the endometrium, a process known as endometrial receptivity. Loss of E-cadherin expression is essential during the process, while the expression level of the… read more here.
Keywords: cadherin expression; cadherin cadherin; receptivity; endometrial receptivity ... See more keywords
TM4SF19 aggravates LPS-induced attenuation of vascular endothelial cell adherens junctions by suppressing VE-cadherin expression.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.08.078
Abstract: Atherosclerosis is a chronic vascular inflammatory disease that initially starts from an arterial intima lesion and endothelial barrier dysfunction. The purpose of this study was to investigate the role of TM4SF19, a recently identified member… read more here.
Keywords: cadherin expression; endothelial cell; adherens junctions; cell adherens ... See more keywords
TGF-β1 up-regulates cadherin-11 expression through Snail: A potential mechanism for human trophoblast cell differentiation.
Sign Up to like & getrecommendations! Published in 2018 at "Cellular signalling"
DOI: 10.1016/j.cellsig.2017.12.004
Abstract: Cadherins are transmembrane proteins that mediate cell-cell adhesion by promoting the formation of adherens junctions. The regulated expression of cadherins is thought to play important roles in both normal and diseased placental development. Cadherin-11, also… read more here.
Keywords: cadherin expression; tgf; expression; trophoblast cell ... See more keywords
Prognostic Role of N‐cadherin Expression in Patients With Invasive Bladder Cancer
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Genitourinary Cancer"
DOI: 10.1016/j.clgc.2017.07.001
Abstract: Background We assessed the role of N‐cadherin as a prognostic biomarker in patients with invasive bladder cancer (BCa) who had undergone radical cystectomy (RC). Patients and Methods The present retrospective single‐center study included 433 BCa… read more here.
Keywords: cadherin expression; patients invasive; expression; cancer ... See more keywords
The effect of the Progesterone-Induced Blocking Factor (PIBF) on E-cadherin expression, cell motility and invasion of primary tumour cell lines.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of reproductive immunology"
DOI: 10.1016/j.jri.2017.10.047
Abstract: In addition to being immunomodulatory, Progesterone-Induced Blocking Factor (PIBF) plays a role in cell cycle regulation and invasion. The full length protein is associated with the pericentriolar satellites and as such, it is crucial for… read more here.
Keywords: pibf; invasion; cadherin expression; cell ... See more keywords
Phosphorylation-dependent stabilization of MZF1 upregulates N-cadherin expression during protein kinase CK2-mediated epithelial-mesenchymal transition
Sign Up to like & getrecommendations! Published in 2018 at "Oncogenesis"
DOI: 10.1038/s41389-018-0035-9
Abstract: Epithelial-mesenchymal transition (EMT) is a critical process in invasion and metastasis of cancer cells. E-cadherin to N-cadherin switching is considered a molecular hallmark of EMT. Recently, we reported that increased CK2 activity fully induces E-cadherin… read more here.
Keywords: cadherin; mesenchymal transition; cadherin expression; epithelial mesenchymal ... See more keywords
ATM mutations and E-cadherin expression define sensitivity to EGFR-targeted therapy in colorectal cancer
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.15211
Abstract: EGFR-targeted therapy is a key treatment approach in patients with RAS wildtype metastatic colorectal cancers (CRC). Still, also RAS wildtype CRC may be resistant to EGFR-targeted therapy, with few predictive markers available for improved stratification… read more here.
Keywords: egfr targeted; cadherin expression; targeted therapy; treatment ... See more keywords
Enhancing E-cadherin expression via promoter-targeted miR-373 suppresses bladder cancer cells growth and metastasis
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.21400
Abstract: Previous studies showed that miR-373 had the capacity to induce tumor suppressor gene E-cadherin expression in prostate cancer cells. However, whether miR-373 can activate the expression of E-cadherin in human bladder cancer (BCa) cells and… read more here.
Keywords: cadherin expression; metastasis; expression; cancer cells ... See more keywords
3D Chromatin Architecture Re-Wiring at the CDH3/CDH1 Loci Contributes to E-Cadherin to P-Cadherin Expression Switch in Gastric Cancer
Sign Up to like & getrecommendations! Published in 2023 at "Biology"
DOI: 10.3390/biology12060803
Abstract: Cadherins are cell–cell adhesion molecules, fundamental for cell architecture and polarity. E-cadherin to P-cadherin switch can rescue adherens junctions in epithelial tumours. Herein, we disclose a mechanism for E-cadherin to P-cadherin switch in gastric cancers.… read more here.
Keywords: cdh1; switch; cadherin expression; cadherin ... See more keywords
E-Cadherin Expression Distinguishes Mouse from Human Hematopoiesis in the Basophil and Erythroid Lineages
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12111706
Abstract: E-cadherin is a key regulator of epithelial cell–cell adhesion, the loss of which accelerates tumor growth and invasion. E-cadherin is also expressed in hematopoietic cells as well as epithelia. The function of hematopoietic E-cadherin is,… read more here.
Keywords: cadherin expression; cadherin; hematopoietic cadherin; hematopoiesis ... See more keywords
Assessment of the Molecular Heterogeneity of E-Cadherin Expression in Invasive Lobular Breast Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14020295
Abstract: Simple Summary Invasive lobular breast cancers (ILCs) are histologically classified by their discohesive growth pattern, due to loss of the cell adhesion glycoprotein E-cadherin (CDH1), which arises via mutation in CDH1 in around half of… read more here.
Keywords: cadherin expression; expression; invasive lobular; lobular breast ... See more keywords