Articles with "cadm1" as a keyword



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Comparison of SynCAM1/CADM1 PDZ interactions with MUPP1 using mammalian and bacterial pull‐down systems

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Published in 2020 at "Brain and Behavior"

DOI: 10.1002/brb3.1587

Abstract: Synaptic cell adhesion molecule 1 (SynCAM1) also known as cell adhesion molecule 1 (CADM1) is a transmembrane cell adhesion protein that operates in a variety of physiological and pathological cellular contexts, and its interaction with… read more here.

Keywords: comparison syncam1; syncam1 cadm1; cadm1 pdz; cell adhesion ... See more keywords
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Comparative expression of cell adhesion molecule1 (CADM1) in the testes of experimental mice and some farm animals.

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Published in 2019 at "Acta histochemica"

DOI: 10.1016/j.acthis.2019.151456

Abstract: Cell adhesion molecule1 (CADM1) is a member of the immunoglobulin superfamily (IGSF) that has been found in mammalian testis and plays a substantial role in cell-to-cell interaction via either hemophilic (between spermatogenic cells) or heterophilic… read more here.

Keywords: testis; elongated spermatids; cell adhesion; expression ... See more keywords
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CADM1 Overexpression and CD7 Downregulation in Strongyloides stercoralis and HTLV-1 Coinfection as Possible Markers for Adult T-cell Leukemia/Lymphoma progression

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Published in 2017 at "Open Forum Infectious Diseases"

DOI: 10.1093/ofid/ofx163.170

Abstract: Abstract Background Human T-cell lymphotropic virus (HTLV-1) is a retrovirus endemic in Latin America, Africa, and Asia. Increasing numbers are being reported in the United States. HTLV-1 causes Adult T-cell Leukemia/Lymphoma (ATL) in 3–5% of… read more here.

Keywords: htlv; cell leukemia; infection; adult cell ... See more keywords
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Abstract PO-118: Novel mechanisms of EGFR-TKI resistance and clonal evolution of lung adenocarcinoma by overexpression of a cell adhesion molecule, CADM1

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Published in 2020 at "Cancer Research"

DOI: 10.1158/1538-7445.tumhet2020-po-118

Abstract: Evolution of cancer and generation of its heterogeneity are most dynamically demonstrated in the process of cancer cells acquiring resistance to molecular targeted therapy. Lung adenocarcinoma is the best solid tumor to which molecular targeted… read more here.

Keywords: lung adenocarcinoma; resistance; cell; cadm1 ... See more keywords
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The CADM1 tumor suppressor gene is a major candidate gene in MDS with deletion of the long arm of chromosome 11.

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Published in 2021 at "Blood advances"

DOI: 10.1182/bloodadvances.2021005311

Abstract: Myelodysplastic syndromes (MDS) represent a heterogeneous group of clonal hematopoietic stem-cell disorders characterized by ineffective hematopoiesis leading to peripheral cytopenias and in a substantial proportion of cases to acute myeloid leukemia. The deletion of the… read more here.

Keywords: deletion long; suppressor; gene; cadm1 ... See more keywords
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miR-21 enhances cardiac fibrotic remodeling and fibroblast proliferation via CADM1/STAT3 pathway

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Published in 2017 at "BMC Cardiovascular Disorders"

DOI: 10.1186/s12872-017-0520-7

Abstract: BackgroundCardiac fibrosis play a key role in the atrial fibrillation pathogenesis but the underlying potential molecular mechanism is still understood. However, potential mechanisms for miR-21 upregulation and its role in cardiac fibrosis remain unclear. The… read more here.

Keywords: cardiac fibrotic; fibroblast proliferation; mir; proliferation ... See more keywords
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Possible Therapeutic Utility of anti-Cell Adhesion Molecule 1 Antibodies for Malignant Pleural Mesothelioma

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Published in 2022 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2022.945007

Abstract: Malignant pleural mesothelioma (MPM) is a highly aggressive malignant tumor, and the effective therapeutic drugs are limited. Thus, the establishment of novel therapeutic method is desired. Considerable proportion of MPMs are shown to express cell… read more here.

Keywords: possible therapeutic; cell; malignant pleural; pleural mesothelioma ... See more keywords
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Analysis of the key ligand receptor CADM1_CADM1 in the regulation of thyroid cancer based on scRNA-seq and bulk RNA-seq data

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Published in 2022 at "Frontiers in Endocrinology"

DOI: 10.3389/fendo.2022.969914

Abstract: Introduction Advanced papillary thyroid cancer (PTC) has a poor prognosis, 60~70% of which become radio iodine refractory (RAI-R), but the molecular markers that assess PTC progress to advanced PTC remain unclear. Meanwhile, current targeted therapies… read more here.

Keywords: ligand receptor; seq; ptc; cadm1 cadm1 ... See more keywords
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MicroRNA-214 promotes the EMT process in melanoma by downregulating CADM1 expression

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Published in 2020 at "Molecular Medicine Reports"

DOI: 10.3892/mmr.2020.11446

Abstract: Melanoma is a malignant skin cancer type associated with a high mortality rate, but its treatment is currently not ideal. Both microRNA (miR)-214 and cell adhesion molecule 1 (CADM1) are differentially expressed in melanoma, but… read more here.

Keywords: melanoma; expression; emt process; mir 214 ... See more keywords
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Methylation of CADM1 and MAL together with HPV status in cytological cervical specimens serves an important role in the progression of cervical intraepithelial neoplasia

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Published in 2018 at "Oncology Letters"

DOI: 10.3892/ol.2018.9505

Abstract: Cervical cancer (CC) is the second most common type of cancer affecting the female population. The development of CC takes several years, and involves a precancerous stage known as cervical intraepithelial neoplasia (CIN). A key… read more here.

Keywords: methylation; present study; study; intraepithelial neoplasia ... See more keywords