MCU Upregulation Overactivates Mitophagy by Promoting VDAC1 Dimerization and Ubiquitination in the Hepatotoxicity of Cadmium
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Science"
DOI: 10.1002/advs.202203869
Abstract: Cadmium (Cd) is a high‐risk pathogenic toxin for hepatic diseases. Excessive mitophagy is a hallmark in Cd‐induced hepatotoxicity. However, the underlying mechanism remains obscure. Mitochondrial calcium uniporter (MCU) is a key regulator for mitochondrial and… read more here.
Keywords: mcu; cadmium; mitophagy; hepatotoxicity ... See more keywords
Tunneling Nanotube‐Mediated Transcellular Autophagy Alleviates Cadmium Induced Hepatocyte Injury
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202502793
Abstract: Cadmium (Cd) exposure is strongly linked to various diseases and dysregulation of autophagy is a pivotal mechanism in Cd toxicity. Targeted autophagy strategies are promising for the treatment of autophagy dysregulation‐related diseases, including Cd poisoning.… read more here.
Keywords: tunneling nanotube; cadmium; mediated transcellular; transcellular autophagy ... See more keywords
Synthesis and preliminary biological evaluation of antibacterial and antifungal 5-arylidene tetramic acid-cadmium(II) complexes.
Sign Up to like & getrecommendations! Published in 2021 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202100305
Abstract: The synthesis and biological evaluation of 5-arylidene-N-acetyl-tetramic acids cadmium(II) complexes are reported. Eleven novel compounds were prepared, characterized by nuclear magnetic resonance experiments and screened for their antimicrobial activity against five bacterial species (Escherichia coli,… read more here.
Keywords: antibacterial antifungal; biological evaluation; cadmium complexes; arylidene ... See more keywords
Synthesized nanoliposome‐encapsulated kaempferol attenuates liver health parameters and gene expression in mice challenged by cadmium‐induced toxicity
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Applied Biochemistry"
DOI: 10.1002/bab.2368
Abstract: In the present research, we encapsulated a flavonoid called kaempferol into nanoliposomal structures and the health‐promoting effects of synthesized nanoliposome‐loaded kaempferol (NLK) were evaluated in mice challenged by cadmium‐induced . The NLK characteristics, such as… read more here.
Keywords: kaempferol; cadmium induced; challenged cadmium; cadmium ... See more keywords
Aqueous‐alcoholic Ferulla extract reduces memory impairments in rats exposed to cadmium chloride
Sign Up to like & getrecommendations! Published in 2021 at "Brain and Behavior"
DOI: 10.1002/brb3.2285
Abstract: Cadmium (Cd) is the most dangerous heavy metal that is becoming more widespread in nature as a result of industrial activities. One of the toxic effects of Cd on the body is its neurological effect.… read more here.
Keywords: ferulla extract; ferulla; aqueous alcoholic; cadmium ... See more keywords
The effect of food processing on the bioaccessibility of cadmium and micronutrients from whole wheat porridge
Sign Up to like & getrecommendations! Published in 2024 at "Cereal Chemistry"
DOI: 10.1002/cche.10778
Abstract: Wheat porridge contributes to the intake of micronutrients but can also be a route of the toxic heavy metal, cadmium. This study aimed to determine the effect of processing on micronutrients, cadmium dialyzability, and cellular… read more here.
Keywords: wheat porridge; cadmium; bioaccessibility; bioaccessibility cadmium ... See more keywords
Zinc and Cadmium Complexes of Pyridinemethanol Carboxylates: Metal Carboxylate Zwitterions and Metal-Organic Frameworks.
Sign Up to like & getrecommendations! Published in 2020 at "ChemPlusChem"
DOI: 10.1002/cplu.202000175
Abstract: The heterofunctional lactone furo[3,4-b]pyridin-5(7H)-one (L1 ) undergoes a coordination-induced ring-opening reaction with Zn(NO3 )2 ⋅ 6H2 O to yield the zwitterionic [Zn(L1 ')2 (H2 O)2 ] (1, L1 '=2-(hydroxymethyl)nicotinate) with an uncoordinated carboxylate. The same reaction… read more here.
Keywords: complexes pyridinemethanol; cadmium complexes; carboxylates metal; cadmium ... See more keywords
Short-Term Ageing of Pod-Derived Biochar Reduced Soil Cadmium Mobility and Ameliorated Cadmium Toxicity to Soil Enzymes and Tomato.
Sign Up to like & getrecommendations! Published in 2020 at "Environmental toxicology and chemistry"
DOI: 10.1002/etc.4958
Abstract: Contamination of agricultural soil with Cd has become a global concern because of its adverse effects on eco-health and food safety. Soil amendments with biochar have become one of the phytotechnology to reduce soil metal… read more here.
Keywords: biochar; soil enzymes; toxicity; cadmium ... See more keywords
Effects of aging on cadmium concentrations and renal dysfunction in inhabitants in cadmium‐polluted regions in Japan
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.3455
Abstract: The absorption of cadmium (Cd) may lead to Cd‐related diseases such as renal tubular dysfunction and bone disease, and it is known to take around 10–30 years to reduce Cd concentrations to half their original levels.… read more here.
Keywords: renal dysfunction; age; dysfunction; indicators renal ... See more keywords
Epiproteome profiling of cadmium‐transformed human bronchial epithelial cells by quantitative histone post‐translational modification–enzyme‐linked immunosorbent assay
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.3597
Abstract: Cadmium (Cd), a carcinogenic toxic metal, is pervasively distributed in the soil, water and air. Chronic exposure to Cd has been correlated to lung disease development including cancers. Although many studies have been conducted to… read more here.
Keywords: post translational; epiproteome profiling; cadmium; histone post ... See more keywords
Renal tubular dysfunction and cancer mortality in the Japanese general population living in cadmium‐non‐contaminated areas
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.4304
Abstract: The relationship between cadmium exposure, exposure‐related renal tubular dysfunction, and mortality have been reported, mainly in the residents of Cd‐contaminated areas in Japan. The aim of this study was to establish the cause–effect relationship between… read more here.
Keywords: contaminated areas; non contaminated; cadmium; renal tubular ... See more keywords