Automated lifespan determination across Caenorhabditis strains and species reveals assay-specific effects of chemical interventions
Sign Up to like & getrecommendations! Published in 2019 at "GeroScience"
DOI: 10.1007/s11357-019-00108-9
Abstract: The goal of the Caenorhabditis Intervention Testing Program is to identify robust and reproducible pro-longevity interventions that are efficacious across genetically diverse cohorts in the Caenorhabditis genus. The project design features multiple experimental replicates collected… read more here.
Keywords: caenorhabditis; caenorhabditis strains; lifespan determination; across caenorhabditis ... See more keywords
Improving skeleton algorithm for helping Caenorhabditis elegans trackers
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-79430-8
Abstract: One of the main problems when monitoring Caenorhabditis elegans nematodes (C. elegans) is tracking their poses by automatic computer vision systems. This is a challenge given the marked flexibility that their bodies present and the… read more here.
Keywords: helping caenorhabditis; caenorhabditis; caenorhabditis elegans; algorithm helping ... See more keywords
Vertical transmission in Caenorhabditis nematodes of RNA molecules encoding a viral RNA-dependent RNA polymerase
Sign Up to like & getrecommendations! Published in 2019 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1903903116
Abstract: Significance In organisms composed of a single cell, RNAs of viral origin may be transmitted to daughter cells at cell division without passing through an extracellular virion stage. These RNAs usually encode an RNA-dependent RNA… read more here.
Keywords: caenorhabditis; rna dependent; rna; vertical transmission ... See more keywords
Transcriptomic analyses reveal groups of co-expressed, syntenic lncRNAs in four species of the genus Caenorhabditis
Sign Up to like & getrecommendations! Published in 2019 at "RNA Biology"
DOI: 10.1080/15476286.2019.1572438
Abstract: ABSTRACT Long non-coding RNAs (lncRNAs) are a heterogeneous class of genes that do not code for proteins. Since lncRNAs (or a fraction thereof) are expected to be functional, many efforts have been dedicated to catalog… read more here.
Keywords: caenorhabditis; reveal groups; groups expressed; analyses reveal ... See more keywords
Synaptogenesis: unmasking molecular mechanisms using Caenorhabditis elegans.
Sign Up to like & getrecommendations! Published in 2023 at "Genetics"
DOI: 10.1093/genetics/iyac176
Abstract: The nematode Caenorhabditis elegans is a research model organism particularly suited to the mechanistic understanding of synapse genesis in the nervous system. Armed with powerful genetics, knowledge of complete connectomics, and modern genomics, studies using… read more here.
Keywords: unmasking molecular; caenorhabditis; molecular mechanisms; caenorhabditis elegans ... See more keywords
Neural Circuitry That Mediates Behavior Governing the Tradeoffs Between Survival and Reproduction in Caenorhabditis elegans.
Sign Up to like & getrecommendations! Published in 2017 at "Integrative and comparative biology"
DOI: 10.1093/icb/icx077
Abstract: In all outcrossing sexual species there is a mechanism that brings two parents together. For animals, this reproductive requirement may at times conflict with other needs, such as foraging for food. This tension has been… read more here.
Keywords: reproduction; caenorhabditis; neural circuitry; caenorhabditis elegans ... See more keywords
Recurrent but Short-Lived Duplications of Centromeric Proteins in Holocentric Caenorhabditis Species
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Biology and Evolution"
DOI: 10.1093/molbev/msac206
Abstract: Centromeric histones (CenH3s) are essential for chromosome inheritance during cell division in most eukaryotes. CenH3 genes have rapidly evolved and undergone repeated gene duplications and diversification in many plant and animal species. In Caenorhabditis, two… read more here.
Keywords: kinetochore protein; caenorhabditis; hcp; short lived ... See more keywords
Widespread transposon co-option in the Caenorhabditis germline regulatory network
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1101/2022.01.21.477252
Abstract: The movement of selfish DNA elements can lead to widespread genomic alterations with potential to create novel functions. Here we show that transposon expansions in Caenorhabditis nematodes led to extensive rewiring of germline transcriptional regulation.… read more here.
Keywords: network; caenorhabditis; widespread transposon; option caenorhabditis ... See more keywords
Classification of Caenorhabditis Elegans Locomotion Behaviors with Eigenfeature-Enhanced Long Short-Term Memory Networks.
Sign Up to like & getrecommendations! Published in 2022 at "IEEE/ACM transactions on computational biology and bioinformatics"
DOI: 10.1109/tcbb.2022.3153668
Abstract: The free-living nematode Caenorhabditis elegans is an ideal model for understanding behavior and networks of neurons. Experimental and quantitative analyses of neural circuits and behavior have led to system-level understanding of behavioral genetics and process… read more here.
Keywords: eigenfeature enhanced; caenorhabditis elegans; caenorhabditis; elegans locomotion ... See more keywords
Antiageing properties of Damaurone D in Caenorhabditis elegans
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Pharmacy and Pharmacology"
DOI: 10.1111/jphp.12979
Abstract: This study was conducted to evaluate the longevity potential of damaurone D (DaD), a component of the damask rose, in the animal model Caenorhabditis elegans. read more here.
Keywords: caenorhabditis; properties damaurone; caenorhabditis elegans; pharmacology ... See more keywords
Genome-wide characterization, evolution, structure, and expression analysis of the F-box genes in Caenorhabditis
Sign Up to like & getrecommendations! Published in 2021 at "BMC Genomics"
DOI: 10.1186/s12864-021-08189-7
Abstract: Background F-box proteins represent a diverse class of adaptor proteins of the ubiquitin-proteasome system (UPS) that play critical roles in the cell cycle, signal transduction, and immune response by removing or modifying cellular regulators. Among… read more here.
Keywords: box gene; caenorhabditis; gene; evolution ... See more keywords