HTRA1 Regulates Subclinical Inflammation and Activates Proangiogenic Response in the Retina and Choroid
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DOI: 10.3390/ijms231810206
Abstract: High-temperature requirement A1 (HtrA1) has been identified as a disease-susceptibility gene for age-related macular degeneration (AMD) including polypoidal choroidal neovasculopathy (PCV). We characterized the underlying phenotypic changes of transgenic (Tg) mice expressing ubiquitous CAG promoter… read more here.
Keywords: htra1; subclinical inflammation; cag htra1; mice ... See more keywords