Articles with "cag trinucleotide" as a keyword



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Molecular insights into the interaction of CAG trinucleotide RNA repeats with nucleolin and its implication in polyglutamine diseases

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Published in 2022 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkac532

Abstract: Abstract Polyglutamine (polyQ) diseases are a type of inherited neurodegenerative disorders caused by cytosine–adenine–guanine (CAG) trinucleotide expansion within the coding region of the disease-associated genes. We previously demonstrated that a pathogenic interaction between expanded CAG… read more here.

Keywords: interaction; rna; molecular insights; cag ... See more keywords