Host immune response mediates changes in cagA copy number and virulence potential of Helicobacter pylori
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DOI: 10.1080/19490976.2022.2044721
Abstract: ABSTRACT Helicobacter pylori is the major risk factor for gastric cancer. H. pylori harboring the type IV secretion system (T4SS) and its effector CagA encoded on the cag pathogenicity Island (cagPAI) increases the risk. H.… read more here.
Keywords: caga copy; copy number; pylori;
Dynamic Expansion and Contraction of cagA Copy Number in Helicobacter pylori Impact Development of Gastric Disease
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DOI: 10.1128/mbio.01779-16
Abstract: ABSTRACT Infection with Helicobacter pylori is a major risk factor for development of gastric disease, including gastric cancer. Patients infected with H. pylori strains that express CagA are at even greater risk of gastric carcinoma.… read more here.
Keywords: caga copy; gastric disease; caga; disease ... See more keywords