Articles with "caix expressing" as a keyword



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New approach of delivering cytotoxic drugs towards CAIX expressing cells: A concept of dual-target drugs.

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Published in 2017 at "European journal of medicinal chemistry"

DOI: 10.1016/j.ejmech.2016.10.037

Abstract: Carbonic anhydrase IX (CAIX) is a hypoxia-regulated and tumor-specific protein that maintains the pH balance of cells. Targeting CAIX might be a valuable approach for specific delivery of cytotoxic drugs, thereby reducing normal tissue side-effects.… read more here.

Keywords: dual target; caix expressing; target; cytotoxic drugs ... See more keywords