BIX-01294 sensitizes renal cancer Caki cells to TRAIL-induced apoptosis through downregulation of survivin expression and upregulation of DR5 expression
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DOI: 10.1038/s41420-018-0035-8
Abstract: BIX-01294 (BIX), a G9a histone methyltransferase inhibitor, has been reported for its anti-proliferative and anticancer activities against various cancer cell lines. In this study, we investigated whether BIX could sensitize TRAIL-mediated apoptosis in various cancer… read more here.
Keywords: apoptosis; induced apoptosis; expression; dr5 ... See more keywords