The vitamin D analogue calcipotriol promotes an anti-tumorigenic phenotype of human pancreatic CAFs but reduces T cell mediated immunity
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-74368-3
Abstract: The pancreatic tumour stroma is composed of phenotypically heterogenous cancer-associated fibroblasts (CAFs) with both pro- and anti-tumorigenic functions. Here, we studied the impact of calcipotriol, a vitamin D3 analogue, on the activation of human pancreatic… read more here.
Keywords: cafs; anti tumorigenic; human pancreatic; vitamin analogue ... See more keywords
Calcipotriol inhibits psoriasis-like angiogenic features in K14-VEGF transgenic mice
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Dermatology"
DOI: 10.1684/ejd.2022.4230
Abstract: Background Angiogenesis is both a notable characteristic of psoriasis and a key driver of its pathogenesis. Calcipotriol has been used for the treatment of psoriasis for several decades, yet few studies have focused on its… read more here.
Keywords: vegf; mice; vegf transgenic; k14 vegf ... See more keywords