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   Articles with "calcium" as a keyword



Localization, Morphologic Features, and Chemical Composition of Calciphylaxis-Related Skin Deposits in Patients With Calcific Uremic Arteriolopathy.

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recommendations! Published in 2019 at "JAMA dermatology"

DOI: 10.1001/jamadermatol.2019.0381

Abstract: Importance Calcific uremic arteriolopathy (CUA), a rare, potentially fatal, disease with calcium deposits in skin, mostly affects patients with end-stage renal disease who are receiving dialysis. Chemical composition and structure of CUA calcifications have been… read more here.

Keywords: uremic arteriolopathy; microscopy; chemical composition; localization morphologic ... See more keywords

Impact of Common Vitamin D-Binding Protein Isoforms on Supplemental Vitamin D3 and/or Calcium Effects on Colorectal Adenoma Recurrence Risk: A Secondary Analysis of a Randomized Clinical Trial.

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recommendations! Published in 2023 at "JAMA oncology"

DOI: 10.1001/jamaoncol.2022.6924

Abstract: Importance Variants in the vitamin D-binding protein (DBP) gene (GC) encode DBP isoforms that may affect vitamin D metabolism. However, whether these isoforms modify the effects of vitamin D3 and/or calcium supplementation on colorectal adenoma… read more here.

Keywords: vitamin calcium; calcium; adenoma recurrence; vitamin ... See more keywords

Association of Dietary and Supplementary Calcium Intake With Age-Related Macular Degeneration: Age-Related Eye Disease Study Report 39

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recommendations! Published in 2019 at "JAMA Ophthalmology"

DOI: 10.1001/jamaophthalmol.2019.0292

Abstract: Importance Previous studies of the role of dietary and supplementary calcium in age-related macular degeneration (AMD) have produced mixed results, suggesting that supplementation and decreased dietary intake are both harmful. Objective To evaluate the association… read more here.

Keywords: intake; age related; supplementary calcium; calcium intake ... See more keywords

Vitamin D, calcium or a combination of vitamin D and calcium for the treatment of nutritional rickets in children

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recommendations! Published in 2017 at "Cochrane Database of Systematic Reviews"

DOI: 10.1002/14651858.cd012581

Abstract: Background Nutritional rickets is a disease which affects children, especially in low- and middle-income countries. It causes problems such as skeletal deformities and impaired growth. The most common cause of nutritional rickets is vitamin D… read more here.

Keywords: calcium; vitamin calcium; nutritional rickets; certainty evidence ... See more keywords

LINC00998‐encoded micropeptide SMIM30 promotes the G1/S transition of cell cycle by regulating cytosolic calcium level

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recommendations! Published in 2022 at "Molecular Oncology"

DOI: 10.1002/1878-0261.13358

Abstract: The biological functions of short open reading frame (sORF)‐encoded micropeptides remain largely unknown. Here, we report that LINC00998, a previously annotated lncRNA, was upregulated in multiple cancer types and the sORF on LINC00998 encoded a… read more here.

Keywords: cytosolic calcium; cell; calcium; calcium level ... See more keywords
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Molecular dynamics provides new insights into the mechanism of calcium signal transduction and interdomain interactions in cardiac troponin

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recommendations! Published in 2020 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.13009

Abstract: Understanding the regulation of cardiac muscle contraction at a molecular level is crucial for the development of therapeutics for heart conditions. Despite the availability of atomic structures of the protein components of cardiac muscle thin… read more here.

Keywords: molecular dynamics; cardiac muscle; cardiac troponin; tnc ... See more keywords

Macrophage Intracellular “Calcium Oscillations” Triggered Through In Situ Mineralization Regulate Bone Immunity to Facilitate Bone Repair

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recommendations! Published in 2024 at "Advanced Functional Materials"

DOI: 10.1002/adfm.202316224

Abstract: Bioceramics are vital for treating bone defects, and bioactive glasses (exemplified by 45S5) and calcium phosphate ceramics (CaPs, exemplified by tricalcium phosphate [β‐TCP]) are extensively explored. β‐TCP exhibits superior biocompatibility, degradability, and osteoconductive properties than… read more here.

Keywords: repair; calcium; situ mineralization; bone ... See more keywords

Photocurrent‐Directed Immunoregulation Accelerates Osseointegration through Activating Calcium Influx in Macrophages

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recommendations! Published in 2024 at "Advanced Functional Materials"

DOI: 10.1002/adfm.202406095

Abstract: Early osteoimmune microenvironment disorder at the interface between bone and implant can lead to implant loosening, which prolongs patient convalescence, exacerbates postoperative complications, and potentially results in implant failure. The timely regulation of macrophages primarily… read more here.

Keywords: macrophage polarization; calcium; calcium influx; osteoimmune microenvironment ... See more keywords

An Endoplasmic Reticulum‐Targeting and Calcium Metabolism‐Disrupting Nanodrug Enhances Tumor Photodynamic Immunotherapy

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recommendations! Published in 2025 at "Advanced Functional Materials"

DOI: 10.1002/adfm.202424108

Abstract: The inefficient clearance of deep tumors and metastatic lesions greatly hinders the clinical applications of photodynamic therapy (PDT). Inducing robust immunogenic cell death (ICD) is crucial for improving PDT outcomes, as ICD‐mediated T‐cell adaptive immune… read more here.

Keywords: disrupting nanodrug; endoplasmic reticulum; photodynamic immunotherapy; calcium ... See more keywords

Inhibition of Sympathetic Activation by Delivering Calcium Channel Blockers from a 3D Printed Scaffold to Promote Bone Defect Repair

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recommendations! Published in 2022 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.202200785

Abstract: Enhancing osteogenesis by promoting neural network reconstruction and neuropeptide release is considered to be an attractive strategy for repairing of critical size bone defects. However, traumatic bone defects often activate the damaged sympathetic nervous system… read more here.

Keywords: calcium; bone; bone defect; activation ... See more keywords

Engineering H2O2 and O2 Self‐Supplying Nanoreactor to Conduct Synergistic Chemiexcited Photodynamic and Calcium‐Overloaded Therapy in Orthotopic Hepatic Tumors

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recommendations! Published in 2022 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.202201613

Abstract: Photodynamic therapy (PDT) is traditionally ineffective for deeply embedded tumors due to the poor penetration depth of the excitation light. Chemiluminescence resonance energy transfer (CRET) has emerged as a promising mode of PDT without external… read more here.

Keywords: calcium; overloaded therapy; therapy orthotopic; therapy ... See more keywords