SEC‐SAXS and HDX‐MS: A powerful combination. The case of the calcium‐binding domain of a bacterial toxin
Sign Up to like & getrecommendations! Published in 2018 at "Biotechnology and Applied Biochemistry"
DOI: 10.1002/bab.1577
Abstract: Small‐angle X‐ray scattering (SAXS) is a relatively simple experimental technique that provides information on the global conformation of macromolecules in solution, be they fully structured, partially, or extensively unfolded. Size exclusion chromatography in line with… read more here.
Keywords: combination; case calcium; calcium binding; saxs ... See more keywords
Calcium‐binding proteins typify the dopaminergic neuronal subtypes in the ventral tegmental area of zebra finch, Taeniopygia guttata
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.25352
Abstract: Calcium‐binding proteins (CBPs) regulate neuronal function in midbrain dopamine (DA)‐ergic neurons in mammals by buffering and sensing the intracellular Ca2+, and vesicular release. In birds, the equivalent set of neurons are important in song learning,… read more here.
Keywords: calbindin calretinin; calcium binding; calretinin; tegmental area ... See more keywords
Calcium‐binding protein and some neuropeptides in the retina of Octopus vulgaris: A morpho‐histochemical study
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26570
Abstract: The existence of both calcium‐binding proteins (CBPs) and neuropeptides in the retina and brain of various species of vertebrates and invertebrates is well documented. Octopus retina is particularly interesting because it represents a case of… read more here.
Keywords: protein; calcium binding; neuropeptides retina; octopus retina ... See more keywords
The prognostic value of S100A calcium binding protein family members in predicting severe forms of COVID-19
Sign Up to like & getrecommendations! Published in 2022 at "Inflammation Research"
DOI: 10.1007/s00011-022-01545-7
Abstract: Background Excessive inflammation has been implicated in the immunopathogenesis of coronavirus disease 2019 (COVID-19). In the current study, the involvement of S100 calcium binding protein S100A4, S100A9, and S100A10 in the inflammatory settings of COVID-19… read more here.
Keywords: s100a9; binding protein; covid; s100a10 ... See more keywords
Biophysical characterization of Ca2+-binding of S100A5 and Ca2+-induced interaction with RAGE.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2016.12.143
Abstract: S100A5 is a calcium-binding protein of S100 family, which represents a major ligand to the receptor for advanced glycation end product (RAGE), a pattern recognition receptor engaged in diverse pathological processes. Here we have characterized… read more here.
Keywords: calcium binding; biophysical characterization; rage; ca2 ... See more keywords
Insight into the binding affinity of thiourea in the calcium binding pocket of proteinase K, through high resolution X-ray crystallography.
Sign Up to like & getrecommendations! Published in 2019 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2019.103443
Abstract: Proteinase K is a stable serine protease, crystallized and extensively used in the study of molecular interactions at the atomic level. During the current study, crystal structure of proteinase K with thiourea (TU) was solved… read more here.
Keywords: calcium binding; thiourea; proteinase; calcium ... See more keywords
A mongolian pine specific endoplasmic reticulum localized CALMODULIN-LIKE calcium binding protein enhances arabidopsis growth.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of plant physiology"
DOI: 10.1016/j.jplph.2018.04.006
Abstract: Stress-adapted wild plants are natural sources of novel genes for molecular breeding. Here, we conducted a transcriptional analysis of Pinus sylvestris var. mongolica Litv, an evergreen pine in northeastern China, to identify a novel CALMODULIN-LIKE… read more here.
Keywords: protein; calmodulin like; calcium binding; endoplasmic reticulum ... See more keywords
The S100 calcium-binding protein A11 promotes hepatic steatosis through RAGE-mediated AKT-mTOR signaling.
Sign Up to like & getrecommendations! Published in 2021 at "Metabolism: clinical and experimental"
DOI: 10.1016/j.metabol.2021.154725
Abstract: RATIONALE Nonalcoholic fatty liver disease (NAFLD), the most common cause of chronic liver disease, has become an increasingly severe public health problem. However, the underlying mechanism for the occurrence and development of NAFLD remains largely… read more here.
Keywords: protein; protein a11; calcium binding; s100 calcium ... See more keywords
1,25-Dihydroxyvitamin-D3 induces brain proteomic changes in cuprizone mice during remyelination involving calcium proteins
Sign Up to like & getrecommendations! Published in 2018 at "Neurochemistry International"
DOI: 10.1016/j.neuint.2017.08.008
Abstract: &NA; Dietary supplementation of vitamin D is commonly recommended to patients with multiple sclerosis. We recently found that high‐dose of the hormonally active 1,25‐dihydroxyvitamin‐D3 (1,25D) promotes myelin repair in the cuprizone model for de‐ and… read more here.
Keywords: calcium binding; remyelination; calretinin; mice remyelination ... See more keywords
The Activation of Protein Kinase A by the Calcium-Binding Protein S100A1 Is Independent of Cyclic AMP
Sign Up to like & getrecommendations! Published in 2017 at "Biochemistry"
DOI: 10.1021/acs.biochem.7b00117
Abstract: Biochemical and structural studies demonstrate that S100A1 is involved in a Ca2+-dependent interaction with the type 2α and type 2β regulatory subunits of protein kinase A (PKA) (RIIα and RIIβ) to activate holo-PKA. The interaction… read more here.
Keywords: calcium binding; kinase calcium; activation protein; binding protein ... See more keywords
Computational Exploration and Characterization of Potential Calcium Sensitizing Mutations in Cardiac Troponin C
Sign Up to like & getrecommendations! Published in 2022 at "Journal of chemical information and modeling"
DOI: 10.1021/acs.jcim.2c01132
Abstract: Calcium-dependent heart muscle contraction is regulated by the cardiac troponin protein complex (cTn) and specifically by the N-terminal domain of its calcium binding subunit (cNTnC). cNTnC contains one calcium binding site (site II), and altered… read more here.
Keywords: calcium binding; calcium; cntnc; computational exploration ... See more keywords