Isoliensinine Eliminates Afterdepolarizations Through Inhibiting Late Sodium Current and L-Type Calcium Current
Sign Up to like & getrecommendations! Published in 2020 at "Cardiovascular Toxicology"
DOI: 10.1007/s12012-020-09597-z
Abstract: Isoliensinine (IL) extracted from lotus seed has a good therapeutic effect on cardiovascular diseases. However, its effect on ion channels of ventricular myocytes is still unclear. We used whole-cell patch-clamp techniques to detect the effects… read more here.
Keywords: late sodium; sodium current; calcium current; type calcium ... See more keywords
Alteration of Action Potential during Early Ischemia in the Heart
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DOI: 10.1016/j.bpj.2016.11.2176
Abstract: Ischemic heart disease still is the most common cause of death in the world. Metabolic inhibition is typical for ischemic heart disease and heart failure and we investigated the effect of induced early ischemia and… read more here.
Keywords: calcium current; heart; ischemia; action potential ... See more keywords