Effect of heat stress and Hsp90 inhibition on T-type calcium currents and voltage-dependent potassium currents in leydig cells.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of thermal biology"
DOI: 10.1016/j.jtherbio.2019.05.022
Abstract: Heat can trigger testicular damage and impair fertility. Leydig cells produce testosterone in response to stimulation by luteinizing hormone (LH), which induces Ca2+ entry and K+ efflux through ion channels in their plasma membrane. Considering… read more here.
Keywords: type calcium; currents voltage; stress; calcium currents ... See more keywords
The Glycolytic Metabolite, Fructose-1,6-bisphosphate, Blocks Epileptiform Bursts by Attenuating Voltage-Activated Calcium Currents in Hippocampal Slices
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2018.00168
Abstract: Manipulation of metabolic pathways (e.g., ketogenic diet (KD), glycolytic inhibition) alters neural excitability and represents a novel strategy for treatment of drug-refractory seizures. We have previously shown that inhibition of glycolysis suppresses epileptiform activity in… read more here.
Keywords: fructose bisphosphate; activated calcium; hippocampal slices; voltage activated ... See more keywords
Modulation of G-protein activation, calcium currents and opioid receptor phosphorylation by the pH-dependent antinociceptive agonist NFEPP
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2023.1171855
Abstract: N-(3-fluoro-1-phenethylpiperidine-4-yl)-N-phenyl propionamide is a newly-designed pain killer selectively activating G-protein-coupled mu-opioid receptors (MOR) in acidic injured tissues, and therefore devoid of central side effects which are typically elicited at normal pH values in healthy tissues.… read more here.
Keywords: calcium; calcium currents; phosphorylation dependent; protein ... See more keywords